Gilead Sciences, Inc.

Other

Mark J Bartlett

Rao V Kalla

Jennifer Leigh Cosman

Thao Perry

Richard L Mackman

Dustin S Siegel

Suet Chung Yeung

Julian Andrew Codelli

Joshua J Van Veldhuizen

Jennifer Alissa Loyer-Drew

Jennifer L Cosman Ellis

Jeff A Zablocki

Gary Bruce Phillips

Scott A Mitchell

Seung H Lee

Britton Kenneth Corkey

Musong Kim

Jayaraman Chandrasekhar

Jennifer R Lo

Gayatri Balan

Daniel H Byun

John H Conway

Patrick J Salvo

Yifan Deng

Xianhuang Zeng

Xiaofen Li

Kristyna M Elbel

Elfatih O Elzein

Sundaramoorthi Swaminathan

Hai Yang

Zachary A Kasun

Dmitry Koltun

Eric Q Parkhill

Michael R Mish

Gregory F Chin

Michael O Clarke

Bindu Goyal

Deeba Ensan

Stephen Ho

Scott D Schroeder

Hon Chung Hui

Robert L Watson

David Sperandio

Nathan D Shapiro

Doris T Tang

Kyle C Tamshen

Eifatih Elzein

Compounds and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

Compounds and methods for treatment of viral infections

The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Substituted 6-azabenzimidazole compounds

The present disclosure provides pyrimidine dione compounds of Formula I

CD73 compounds

Provided herein is A compound of Formula I: or a pharmaceutically acceptable salt thereof, wherein the various substituents are described herein.

1′-Cyano nucleoside analogs of Formula I and methods of using said compounds, singly or in combination with additional agents, and salts or pharmaceutical compositions of said compounds for the treatment of viral infections are disclosed.

1′-cyano nucleoside analogs and methods for treatment of viral infections

Compounds having the following Formula I and/or Formula II and methods of their use and preparation are disclosed: 

Therapeutic heterocyclic compounds

Compounds having the following Formula (I), or a pharmaceutically acceptable salt or pharmaceutically acceptable tautomer thereof, and methods of their use and preparation are disclosed: 

Compounds having the following Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use and preparation are disclosed: 

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Castro Valley, CA, United States of America

Mark J Bartlett