Merck + Co., Inc.

Mark G Steiner

Sander G Mills

William H Parsons

Peter J Sinclair

Frederick Wong

Dennis M Zaller

Joung L Goulet

Richard Beresis

Helen M Armstrong

Mark A Holmes

Xingfang Hong

Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such are useful in the prophylaxis and treatment of protein tyrosine kinase-associated disorders, such as immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to play a role, such as cancer, angiogensis, atheroscelerosis, graft rejection, rheumatoid arthritis and psoriasis.

Src kinase inhibitor compounds

Growing community of inventors

East Brunswick, NJ, United States of America

Mark G Steiner