Assembly Biosciences, Inc.

Indiana University

Mark G Bures

Leping Li

Simon Nicolas Haydar

Lee Daniel Arnold

Hans Maag

Samson Francis

William W Turner

William Wilson Turner, Jr

Roopa Rai

Lynne Bannen

Michael Walker

William Turner

The present disclosure provides, in part, 5-membered heteroaryl carboxamide compounds, and pharmaceutical compositions thereof, useful for disruption of HBV core protein assembly, and methods of treating Hepatitis B (HBV) infection.

5-membered heteroaryl carboxamide compounds for treatment of HBV

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound.

Hepatitis b core protein modulators

The present disclosure provides, in part, cyclic sulfamide compounds, and pharmaceutical compositions thereof, useful as modulators of Hepatitis B (HBV) core protein, and methods of treating Hepatitis B (HBV) infection.

Cyclic sulfamide compounds and methods of using same

The present disclosure provides, in part, compounds having allosteric effector properties against Hepatitis B virus Cp. Also provided herein are methods of treating viral infections, such as hepatitis B, comprising administering to a patient in need thereof a disclosed compound of formula: 

Hepatitis B core protein modulators

Growing community of inventors

Carmel, IN, United States of America

Mark G Bures