Nutrition 21, Inc.

Ambi Inc.

Pcb Associates, Inc.

Mark F McCarty

Jan Zielinski

Sheldon S Hendler

Toyoshi Inoguchi

John Gustin

David Michael Rorvik

Phycobilins are disclosed to have prodrug activity as inhibitors of NADPH oxidase activity and are disclosed to be useful in the prophylaxis and/or treatment of medical conditions associated with or linked to an NADPH oxidase activity. Compositions containing phycobilins are described which facilitate the administration of phycobilins.

Compositions for inhibiting NADPH oxidase activity

A method for treating Type II diabetes by administering to an affected individual a combination of chromic tripicolinate and biotin. The two compounds are administered orally or parenterally at in daily dosages which provide between 50 and 1,000 &#x3bc;g of chromium and between 25 &#x3bc;g and 200 mg biotin, the amounts of chromium and biotin being selected together to provide a greater than additive effect.

Chromium/biotin treatment of type II diabetes

The present invention is directed to an arginine-silicate complex and its use in the prevention and treatment of atherosclerosis, as a dietary supplement, and for promotion of structural integrity of bones and cartilage.

Arginine-silicate-inositol complex and use thereof

A method for stabilizing blood glucose levels and reducing the hyperglycemia associated with Type II diabetes. Synthetic chromic tripicolinate is administered either orally or parenterally to a human in need thereof at a dosage of between about 1,000 amd 10,000 micrograms per day.

High-dose chromic picolinate treatment of type II diabetes

Use of calcium taurate as an antihypertensive agent and dietary supplement. The compound is prepared by reacting taurine and calcium in a 2:1 molar ratio. The resulting mixture is diluted with alcohol and the remaining clear filtrate is crystallized. Calcium taurate is taken orally as a nutritional supplement or antihypertensive agent, and can be used as an adjuvant to conventional antihypertensive drugs.

Calcium taurate as a dietary supplement

Arginine silicate inositol complex and use thereof

Use of calcium taurate as an antihypertensive agent and dietary supplement. The compound is prepared by reacting taurine and calcium in a 2:1 molar ratio. The resulting mixture is diluted with alcohol and the remaining clear filtrate is crystallized. Calcium taurate is taken orally as nutritional supplement or antihypertensive agent, and can be used as an adjuvant to conventional antihypertensive drugs.

Calcium taurate and antihypertensive drug for hypertension

A method for treating Type II diabetes by administering to an affected individual a combination of chromic tripicolinate and biotin. The two compounds are administered orally or parenterally at in daily dosages which provide between 50 and 1,000 .mu.g of chromium and between 25 .mu.g and 200 mg biotin, the amounts of chromium and biotin being selected together to provide a greater than additive effect.

Chromium/biotin treatment of Type II diabetes

A method for promoting weight and fat loss comprising administering to an individual in need thereof hydroxycitrate, carnitine and an agent which promotes the rapid intramitochondrial generation of oxaloacetate or induces endogenous production of pyruvate. This method also promotes an increase in lean body mass.

Method for promoting weight and fat loss

A magnesium-taurine compound and its method of synthesis. The compound is synthesized by reacting taurine and magnesium in a 2:1 molar ratio. The resulting mixture is diluted with methanol and the remaining clear filtrate is crystallized from methanol. This compound may be administered orally as a nutritional supplement or may be administered orally or intravenously for treatment of thrombotic or embolic stroke.

Pharmaceutical composition for rapid thrombolytic therapy

A method for treating Type II diabetes by administering to an affected individual a combination of chromic tripicolinate and biotin at doses far beyond the nutritional requirements. The two compounds are administered orally or parenterally at in daily dosages which provide between 1,000 and 10,000 .mu.g of chromium and between 1 mg and 200 mg biotin.

High-dose chromium/biotin treatment of type II diabetes

Magnesium taurate as an adjuvant to rapid thrombolytic therapy

A magnesium-taurine compound and its method of synthesis. The compound is synthesized by reacting taurine and magnesium in a 2:1 molar ratio. The resulting mixture is diluted with methanol and the remaining clear filtrate is crystallized from methanol. This compound may be administered orally as a nutritional supplement or may be administered orally or intravenously for the therapeutic or prophylactic treatment of pre-eclampsia/eclampsia and acute cardiac conditions.

Magnesium taurate for prevention and treatment of pre-eclampsia/eclampsia

An arginine silicate-containing complex and its use in the prevention and treatment of atherosclerosis and as a dietary supplement. The arginine silicate complex is synthesized by combining arginine, potassium silicate and inositol. The complex is administered orally three times per day in an amount ranging from about 250 mg to about 2,500 mg as a preventative or therapeutic agent.

Arginine silicate complex and use thereof

A magnesium-taurine compound and its method of synthesis. the compound is synthesized by reacting taurine and magnesium in a 2:1 molar ratio. The resulting mixture is diluted with methanol and the remaining clear filtrate is crystallized from methanol. This compound may be administered orally as a nutritional supplement or may be administered orally or intravenously for the therapeutic or prophylactic treatment of acute cardiac conditions.

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San Diego, CA, United States of America

Mark F McCarty