University of Pennsylvania

Mark Elliot

Ravinder Reddy

Ari Borthakur

Walter R T Witschey

Luke Macyszyn

Ragini Verma

Steven Brem

Emmanuel Caruyer

Jeremy Lecoeur

Edema invariant tractography methods are provided. The methods include acquiring data using a multishell, high angular resolution diffusion imaging sequence; (ii) modeling the data using a multi-compartment model; and (iii) reconstructing the fibers through a probabilistic tracking algorithm using a fiber orientation distribution which has streamlines fitted to the output of said probabilistic tracking algorithm.

Edema invariant tractography

Methods of, and systems for, simultaneously compensating for external-magnetic-field inhomogeneity as well as radiofrequency magnetic-field inhomogeneity in an MRI system. In one method embodiment, a pulse sequence is applied when the transmitter-reference frequency is delivered on resonance. The pulse sequence includes radiofrequency pulses which may be applied at arbitrary-excitation-flip angles that are not necessarily 90&#xb0; degrees. The pulse sequence also includes spin-locking pulses applied in concert with a refocusing-composite pulse. In another method embodiment, a pulse sequence is applied when the transmitter-reference frequency is delivered off resonance. This off-resonance-pulse sequence includes radiofrequency pulses which may be applied at arbitrary-excitation-flip angles that are not necessarily 90&#xb0; degrees. Sandwiched between the excitation-flip angles are at least two off-resonance-spin-lock pulses applied at an inverse phase and frequency from each other.

System and method for minimizing MRI-imaging artifacts

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Bryn Mawr, PA, United States of America

Mark Elliot