Sibia Neurosciences, Inc.

Merck + Co., Inc.

Other

Dresser Industries, Inc.

The Salk Institute Biotechnology Industrial Associates, Inc.

The Salk Institute Biotechnology/industrial Assoc, Inc.

Mark E Williams

Michael Miller Harpold

Steven B Ellis

Robert Brenner

Ann F McCue

Daniel H Feldman

Arnold Schwartz

Alison Gillespie

Jean Sartor

Kenneth Stauderman

Devices that emit sound audible to nearby animals can include a deflection structure or other support structure and, connected to it, at least one whistle structure. The deflection structure can, for example, be a rain guard, an insect deflector, or a rock deflector. It can, for example, have an air flow surface across which air flows when the vehicle on which it is mounted moves at normal operating speeds, and whistle structures can be activated by the air flow.

Whistle structures

Isolated DNA encoding each of human calcium channel &#x3b1;, &#x3b1;, &#x3b2;- and &#x3b3;-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Human calcium channel compositions and methods

Isolated DNA encoding each of human calcium channel &#x3b1;-, &#x3b1;-, &#x3b2;- and &#x3b3;-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Nucleic acids encoding human calcium channel and methods of use thereof

Isolated DNA encoding each of human calcium channel &agr; -, &agr; -, &bgr;- and &ggr;-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Isolated nucleic acid encoding calcium channel &agr; -subunits, including subunits encoded by nucleic acid that arises as splice variants of primary transcripts, is provided. Cells and vectors containing the nucleic acid and methods for identifying compounds that modulate the activity of calcium channels that contain &agr; -subunits are also provided.

Calcium channel compositions and methods

Isolated DNA encoding each of human calcium channel .alpha..sub.1 -, .alpha..sub.2 -, .beta.- and .gamma.-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Isolated DNA encoding each of human calcium channel .alpha..sub.1 -, .alpha..sub.2 -, .beta.- and .gamma.-subunits, including subunits that arise as splice variants of primary transcripts, is provided. In particular DNA clones encoding each of the .alpha..sub.1A-1, .alpha..sub.1A-2, .alpha..sub.1E-1, .alpha..sub.1C-2, .alpha..sub.1E-3, .beta..sub.3-1, .beta..sub.2C, .beta..sub.2D, .beta..sub.2E and .beta..sub.4 subunits of human calcium channels are provided. Cells and vectors containing the DNA, subunit specific antibodies and nucleic acid probes and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Recombinant human calcium channel .beta..sub.4 subunits

Calcium channel (alpha).sub.1 -subunit and (alpha).sub.2 -subunit-encoding DNA, and related compositions and methods, are provided.

Human calcium channel .alpha..sub.1 -, .alpha..sub.2 -, .beta.- and .gamma.-subunit encoding cDNAs, and related compositions and methods, are provided.

Assays of cells expressing human calcium channels containing

Isolated DNA encoding each of human calcium channel .alpha..sub.1 -, .alpha..sub.2 -, .beta.-and .gamma.-subunits, including subunits that arise as splice variants of primary transcripts, is provided. Cells and vectors containing the DNA and methods for identifying compounds that modulate the activity of human calcium channels are also provided.

Growing community of inventors

Carlsbad, CA, United States of America

Mark E Williams