Warner-lambert Company

Mark E Oehling

Stanley Lech

Chaur-Ming Jan

Felipe Garay

A medicament adsorbate containing corn syrup having contained therein from about 10 to about 90% by weight of the adsorbate of a medicament drug a magnesium trisilicate having a surface area of at least 400 m.sup.2 /g and having a structure with multiple interstitial spaces, and having adsorbed therein from about 0.5 to about 30% by weight of the adsorbate of a medicament drug, wherein the medicament drug is an antihistamine. A reduction in the electrostatic forces between adsorbates is experienced due to the particle size of the adsorbate being in the range greater than 40 to about 800 um, most of the adsorbates prepared being a particle size greater than 150 um, which allows for better processing.

Reduction of electrostatic forces between magnesium trisilicate

A fluidized bed dryer/granulator (10) for coating pellets (P) used in the preparation of pharmaceutical materials, comprises a chamber (11) having a top wall (12) and a bowl (16) at the bottom thereof and an axial air inlet (19) for directing a flow of air axially therethrough, and at least one removable air inlet (20, 21) positioned in the chamber for directing a circumferential flow of air into the chamber to interact with the axial flow to produce an orbital or swirling motion, enhancing the rate of treatment of the material in the chamber.

Growing community of inventors

Stroudsburg, PA, United States of America

Mark E Oehling