Baxter International Inc.

Mark E Loar

Li-Chien Hsu

A composition for coating medical blood contacting surfaces comprises a mixture of an anticoagulant and a defoaming agent. The coating composition is applied by either dipping the device into a solution containing the mixture or by spraying the mixture onto the surface. Alternatively, the surface can be sequentially dip coated and/or sprayed with the individual components. In a preferred embodiment, the anticoagulant is a quaternary ammonium complex of heparin, preferably stearyldimethylbenzyl ammonium heparin, and the antifoaming agent is a mixture of polydimethylsiloxane and silicon dioxide.

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Irvine, CA, United States of America

Mark E Loar