Mycogen Corporation

Nucelis Inc.

Cibus US LLC

Incima US LLC

Coh Inc.

Hycogen Corporation

Cibus Europe, B.v.

Cibus, Inc.

Incima Ipco B.v.

Cibus International, L.p.

Mark E Knuth

Guy A Cardineau

H Ernest Schnepf

Kenneth Edwin Narva

George E Schwab

Michael R Pollard

Tracy Ellis Michaels

Peter R Beetham

Keith A Walker

Stacey Finstad Lee

Greg F W Gocal

Noel M Fong

Joanna Dojillo

Mark Thompson

Rod Aaron Herman

Lisa M Stamp

Paula Diehl

Paula Burmeister

Greg Fw Gocal

Gregory Francis Gocal

Brian A Stockhoff

Gregory Francis William Gocal

Bernhard D Kuebitz

Provided herein compositions and methods for producing isoprenoids, including squalene. In certain aspects and embodiments provided are genetically converted yeast and uses therefore. In some aspects and embodiments, the genetically converted yeast produce isoprenoids, preferably squalene. Also are provided methods of producing squalene using a genetically converted yeast or a non-genetically converted yeast. The invention also provides squalene produced by genetically converted yeast or non-genetically converted yeast.

yeast strains expressing an HMG-CoA reductase having increased activity or expression

The present invention relates to the production of a non-transgenic plant resistant or tolerant to a herbicide of the phosphonomethylglycine family, e.g., glyphosate. The present invention also relates to the use of a recombinagenic oligonucleobase to make a desired mutation in the chromosomal or episomal sequences of a plant in the gene encoding for 5-enol pyruvylshikimate-3-phosphate synthase (EPSPS). The mutated protein, which substantially maintains the catalytic activity of the wild-type protein, allows for increased resistance or tolerance of the plant to a herbicide of the phosphonomethylglycine family, and allows for the substantially normal growth or development of the plant, its organs, tissues or cells as compared to the wild-type plant irrespective of the presence or absence of the herbicide. Additionally the present invention relates to mutantcells that contain mutated EPSPS genes.

EPSPS mutants

Provided herein compositions and methods for producing isoprenoids, including squalene. In certain aspects and embodiments provided are genetically altered yeast and uses therefore. In some aspects and embodiments, the genetically altered yeast produce isoprenoids, preferably squalene. The genetically altered yeast may have alterations in the expression or activity of enzymes involved in squalene production, for example, acetyl-CoA carboxylase (or 'ACCase'), HMG-CoA reductase, squalene epoxidase, and squalene synthase. One or more genes of a genetically altered yeast may be modified by gene repair oligonucleobases. Also are provided methods of producing squalene using a genetically altered yeast. The invention also provides squalene produced by genetically altered yeast.

Production of squalene using yeast

Provided herein are blends oils or fatty acids comprising more than 50% medium chain fatty acids, or the fatty acid alkyl esters thereof, and having low melting points. Such blends are useful as a fuel or as a starting material for the production of, for example, a biodiesel. Also provided genetically altered or modified plants, modified such that the amount of medium chain fatty acids generated by the plant are increased. Further provided is a method of predicting the melting point of a blend of fatty acid methyl esters and the use of such a method for identifying blends suitable for use as, for example, a biodiesel.

Fatty acid blends and uses therefor

Methods and compositions for producing squalene using yeast

The subject invention concerns new classes of pesticidally active proteins and the polynucleotide sequences that encode these proteins. In preferred embodiments, these pesticidal proteins have molecular weights of approximately 40-50 kDa and of approximately 10-15 kDa.

Pesticidal proteins

The subject invention concerns new classes of pesticidally active proteins and the polynucleotide sequences which encode these proteins. More specifically, in preferred embodiments, pesticidal proteins of approximately 40-50 kDa and of approximately 10-15 kDa are used for controlling corn rootworms. Also described are novel pesticidal isolates of

The subject invention concerns new classes of pesticidally active proteins and the polynucleotide sequences that encode these proteins. In preferred embodiments, these pesticidal protein have molecular weights of approximately 40&#x2013;50 kDa and of approximately 10&#x2013;15 kDa.

The subject invention concerns new classes of insecticidal proteins obtainable from, and polynucleotides that encode these proteins. The subject invention also includes transgenic cells and plants that produce these proteins. The proteins are preferably in the 10-15 kDa and 40-50 kDa size range.

Pesticidal toxins

The subject invention pertains to . toxins active against pests. More specifically, the subject invention pertains to truncated Cry6A toxins. These activated toxins are particularly effective for controlling coleopteran pests such as the corn rootworm and the alfalfa weevil.

Bacillus thuringiensis toxins with improved activity

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Poway, CA, United States of America

Mark E Knuth