Finnigan Corporation

Analytica of Branford, Inc.

Mark E Hail

Iain C Mylchreest

Ian C Mylchreest

An electrospray interlace apparatus is disclosed. The apparatus includes an inner needle for transferring a liquid sample to an ionizing region at one end of the needle. A first outer tube surrounds and is spaced apart from the needle to form a cylindrical space through which a flowing liquid may pass. The tube has one end extending beyond the end of the needle to define a mixing volume where the sample and liquid can mix. A second outer tube surrounds the first tube to define a second cylindrical space for flowing a gas past the end of the first tube and needle to focus the electrospray. A voltage is also provided between the tips of the needle and the tubes and an adjacent surface.

Electrospray ion source and interface apparatus and method

An electrospray ion source having a capillary tube for directing ions from an ionizing region to an analyzing region including a skimmer in which the capillary tube is oriented to cause undesolvated droplets to strike the skimmer.

Electrospray ion source with reduced neutral noise and method

An electrospray interface apparatus is disclosed. The apparatus includes an inner needle for transferring a liquid sample to an ionizing region at one end of the needle. A first outer tube surrounds and is spaced apart from the needle to form a cylindrical space through which a flowing liquid may pass. The tube has one end extending beyond the end of the needle to define a mixing volume where the sample and liquid can mix. A second outer tube surrounds the first tube to define a second cylindrical space for flowing a gas past the end of the first tube and needle to focus the electrospray. A voltage is also provided between the tips of the needle and the tubes and an adjacent surface.

An electrospray ion source in which the liquid sample is sheathed with a sheath liquid which reduces the formation of water droplets and minimizes formation of high energy neutrals, resulting in improved signal-to-noise ratios.

Growing community of inventors

Alameda County, CA, United States of America

Mark E Hail