Allegheny-Singer Research Institute

Carnegie Mellon University

Mark Doyle

Robert Biederman

Prahlad G Menon Gopalakrishna

A process and a system for assisting a clinician in identification and evaluation of perfusion characteristics of an organ are disclosed. The process and system may be used to extend clinical diagnosis capabilities by augmenting the ability to analyze perfusion images acquired from a radiology imaging modality through the use of the quantification technology as described. Classification of perfusion characteristics of a region of interest is facilitated through the use of a quantitative spatial perfusion characteristics map. The map is generated by a computing device which applies at least one physics-based image processing technique. This map is displayed on a clinician device for review by the clinician to assist in the spatial identification of perfusion abnormalities.

Physics based image processing and evaluation process of perfusion images from radiology imaging

A method for improved, automated analysis of a data set improves the reliability of the data set by comparing the data set with a model of similar data. The method may be used in applications such as medical imaging, clinical trial participant selection, marketing, security, traffic control, and other applications.

Method and system for recommending a decision based on combined entity modeling

A magnetic resonance imager for forming images of a moving portion of a patient includes imaging coils. The imager includes a computer that causes the imaging coils to apply continuously steady-state free precession to k-space of a magnetic resonance image series of the patient and acquire the image series, and generates images from the image series. A method for forming images of a moving portion of a patient includes the steps of applying continuously steady-state free precession to k-space of a magnetic resonance image series of a patient. There is the step of acquiring the image series. There is the step of generating images from the image series. A method for forming images of a patient includes the steps of triggering a steady-state free precision imaging sequence to an ECG r wave of cardiac cycles of the patient. There is the step of performing the steady-state free precision imaging sequence with imaging coils of a magnetic resonance imaging scanner such that data for a series of k-space data sets associated with the imaging sequence are acquired in a manner that is time resolved through the cardiac cycle, with data acquired over a number of consecutive cardiac cycles. A computer program embodied on a computer readable medium to form an image of a patient with an MRI.

Magnetic resonance imager, method and program which continuously applies steady-state free precession to k-space

An MRI includes imaging coils. The MRI includes receiving coils. The MRI includes a controller in communication with the imaging coils and the receiving coils which controls the imaging coils and the receiving coils to sample k space associated with a patient in a pattern based on prior knowledge of k space data, and which reconstructs an image of the patient from the sampled k space. A method of an MRI includes the steps of acquiring preliminary k space data of a patient indicating the extent of k space data for all receiver channels using imaging and receiving coils. There is the step of determining with a controller which regions of signal associated with the k space are to be targeted by multiple acquisition blades of data with the imaging and receiver coils based on the preliminary k space. There is the step of sampling each of the regions determined by the controller with the blades to obtain k space data. There is the step of storing the k space data in a memory. There is the step of interpolating the k space data to fit in a regular rectangular grid and fitting each separate blade of k space data to the grid with the controller. There is the step of averaging overlapping k space data with the controller. There is the step of reconstructing an image from the k space data. A computer program.

Targeted acquisition using holistic ordering (TACHO) approach for high signal to noise imaging

An imaging apparatus for an object in change includes an MRI system having a first channel which produces images of the object using alternate lines of k-space applied along each of the two phase encoding directions and a computer which combines the individual images into a composite 3D image. The MRI system acquires alternate lines of temporally resolved data along each phase encoding direction. A method for imaging an object in change includes producing an individual image of the object with a first channel of an MRI system using alternate lines of k-space applied for each phase encoding direction, producing an individual image of the object with at least a second channel of the MRI system by acquiring alternate lines of temporally resolved data using alternate lines of k-space, and combining the individual images into a composite 3D image of the object with a computer of the MRI system.

Single coil parallel imaging

An MRI includes imaging coils. The MRI includes receiving coils. The MRI includes a controller causing the imaging coils to produce RF pulses at every repetition time so different parts of a patient are receiving excitation by RF pulses at different rates and k space data are acquired at each repetition time by the receiving coils to form images of the patient with the k space data. A method for an MRI includes the steps of causing with a controller imaging coils to produce RF pulses at every repetition time so different parts of a patient are receiving excitation by RF pulses at different rates. There is the step of acquiring k space data at each repetition time by receiving coils. There is the step of forming images of the patient with the k space data using approaches such as Fourier transformation or filtered back projection.

Steady-state-free-precession (SSFP) magnetic resonance imaging (MRI) and method

A magnetic resonance imager performing images of a patient imager includes imaging coils. The imager includes receiver coils The imager includes a computer that causes the imaging coils to produce a first steady-state free precession excitation slab with respect to a first position regarding a target of the patient during a first repetition time, and a second steady-state free precession excitation slab with respect to a second position different from the first position regarding the target during a second repetition time; and forming a first 3-D dataset of the target associated with the first excitation slab and a second 3-D image dataset of the target associated with the second excitation slab from information received from the receiver coils. The first 3-D image dataset and the second 3-D image dataset, together defining a series of 3-D image datasets for each repetition time; and producing an image of the target from the series of 3-D image datasets. A method for analyzing a patient. A method to evaluate coronary arteries to assess their degree of stenosis. A computer program which, when executed by a computer of a Magnetic Resonance Imager, forms an image of a patient.

Magnetic resonance imager using cylindrical offset region of excitation, and method

An MRI includes at least a singular imaging channel which uses a smoothly varying sampling pattern to sparsely sample k-space as a series of parallel lines over time to acquire data of an object. The MRI includes a computer in communication with the imaging channel that performs a signal processing routine to interpolate the data and fill in points of k-space which were not sampled by the imaging channels and produce an image of the object. A method for using an MRI includes the steps of acquiring data of an object with at least a singular imaging channel of the MRI which uses a smoothly varying sampling pattern to sparsely sample k-space as a series of parallel lines over time. There is the step of performing a signal processing routine with a computer in communication with the imaging channel to interpolate the data and fill in points of k-space which were not sampled by the imaging channels. There is the step of producing an image of the object.

Rapid MRI dynamic imaging using mach

An imaging apparatus for an object in change includes an MRI system having a computer, a first channel and at least a second channel which produce corresponding images of the object in change. The computer combining the individual images into a composite image of the object. Alternatively, the MRI system has at least a first channel which produce an image of the object in change from data acquired in k-space domain in a density of at least &#x2154; that required to satisfy a Nyquist criteria. A method for imaging an object in change includes the steps of producing an individual image of the object in change with a first channel of an MRI system. There is the step of producing an individual image of the object in change with at least a second channel of the MRI system independent of the first channel. There is the step of combining the individual images into a composite image of the object with a computer of the MRI system.

An apparatus for forming an image of a body of a patient. The apparatus comprises an energy source which emits energy that passes through the body or which causes the body to emit energy. The apparatus comprises at least one detector element which receives the energy which has pass through, or originated within the body. The apparatus comprises a computer with a memory in communication with the detector element which stores in the memory angular and timing information relative to the body regarding the energy. The apparatus comprises means for obtaining additional angular and timing information relative to the body regarding the information including the computer-generated steps from a computable readable medium of: acquiring time resolved projective data, either in a sparse manner or in a highly sampled manner, depending on which acquisition aspect of the patient is to be reduced; interpolating either along a circumferential direction or along a temporal direction sparsely sampled data, the interpolation direction being determined by a relative k-space sampling density; applying data filtering either along the circumferential direction or along the temporal direction for highly sampled data, the filtering direction being determined by the relative k-space sampling density; compiling a full radial sampling set from the filtered or interpolated data; and submitting the sampling set for reconstruction. A method for forming an image of a patient.

Method and apparatus for forming an image with dynamic projective data

An MRI includes a cylindrical housing having a long axis in which a patient is positioned essentially in parallel with the long axis of the cylindrical housing. The MRI includes an electromagnetic receiver coil system positioned about a cylindrical housing and aligned with the long axis of the cylindrical housing. The MRI includes an electromagnetic imaging gradients coil system positioned about the cylindrical housing and aligned with the long axis of the cylindrical housing. The MRI includes a main magnet having its north pole and south pole positioned about the housing, which produces a magnetic field through the housing perpendicular to the long axis of the cylindrical housing. A method for examining a patient.

Hybrid MRI and method

An MRI to form an image of a patient includes at least one emitting coil which produces RF pulses and gradients. The MRI includes a controller in communication with the emitting coil for obtaining a steady-state image of the patient, where gradient areas balance to zero for each time repetition (TR) interval, and for causing the emitting coil to produce the RF pulses without interruption during the time repetition interval. The MRI includes at least one receiving coil in communication with the controller which receives the RF pulses and provides the RF pulses to the controller for the controller to obtain the image. A method to form an image of a patient with an MRI. A computer program embodied on a computer readable medium to form an image of a patient with an MRI.

Split-echo with fractional temporal-interpolation

A method for imaging a patient. An apparatus for imaging a patient including a magnetic resonance imager having a controller and a memory in communication with the controller. The controller causes the imager to take a two-dimensional image of the patient which is stored in the memory. The controller identifying locations of interest of the k-space representation of the two-dimensional image, and acquiring a three-dimensional magnetic resonance angiography image based on the locations of interest of the two-dimensional k-space data set.

Growing community of inventors

Wexford, PA, United States of America

Mark Doyle