Amgen Inc.

Medtronic Minimed, Inc.

Other

Mark Dominis Holt

Sheldon B Moberg

Julian D Kavazov

Christopher G Griffin

Francisca Tan-Malecki

Ronald Forster

Scott M Nunn

Susie E Maule

Son C Tran

Paul S Cheney, Ii

Arin N Holecek

Ian B Hanson

Paul F Bente, Iv

R Paul Mounce

Paul H Kovelman

Bradley J Enegren

Melissa D Norton

Robert M Guezuraga

Ron Forster

Alexander Stuart Cairns

Albert D Candioty

Tracy E Grim

Colin A Chong

Joseph M Iglesias

Jason P Adams

Matthew Ryan Garner

Dhairya K Mehta

William K Arnold

Brian Highley

Frederick Charles Houghton

Kraig Kooiman

Tommy C Cushing

Clint Taylor

Milad Girgis

Lance E Shetler

Alec D Bobroff

Philip J Hudak

Sean M Collins

Kevin Richard O'Donnell

John Morgan Bourne

Ruth Marie Tieck

Lance E Shelter

Mathias Romacker

Paul F Bente

Milad T Girgis

Kraig P Kooiman

Paul F Iv Bente

Dhairya Mehta

Paul R Mounce

Iv Paul F Bente

An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

Injector and method of assembly

Method of assembling and filling a drug delivery device

An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

An injector () may include a container () having a wall () with an interior surface () and a seal assembly () with an interior surface (), the interior surfaces () of the wall () and the seal assembly () defining a closed sterile reservoir () filled with a drug product. The injector () may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle () having a point () disposed only partially through the seal assembly () in a storage state, and disposed through the interior surface () of the seal assembly () into the sterile reservoir () in a delivery state. Further, the injection may include an actuator () that is adapted to move the container needle from the storage state to the delivery state.

A vial adapter includes a base having first and second opposing sides, a spike depending from the first side of the base, the spike having a spike passageway, and a connector disposed on the second side of the base, the connector having a connector passageway that is in fluid communication with the spike passageway. The vial adapter may be combined with a vial.

Vial adapter and system

A vial adapter may include first and second sections each having first and second ends joined to form a collar having a central passage in which a neck of a vial may be disposed. Each collar section may have a hook formed at each end, the hooks joined to join the collar sections together. The first ends may have at least one tab depending therefrom and the second ends may have at least one indent formed therein, the tab disposed within the indent with the hooks joined to each other. In addition or instead, the collar may have an inner surface with a groove separating the collar into first and second regions on opposing axial sides of the groove. The first and second regions may be deformable axially into the groove when the collar is acted upon with the neck of the vial in the central passage.

Composition and method for processing prolamin-containing feed source into a low-vitreous gelatinous feedstuff. The feedstuff is fed to ruminant animals for the purpose of potentiating either milk production and/or conception. The feed source can be corn and the ruminant animal can be a bovine, and might be a cow. The method includes processing, by extrusion, a prolamin-containing feed source having a starch-protein matrix within which the included protein is composed of at least 3% percent prolamin. This processing produces a hydrophilic gelatinous feedstuff that has starch and protein content. The hydrophilic low-vitreous gelatinous feedstuff is fed to a ruminant animal. A rumen-retained portion of the fed feedstuff is retained within the rumen of the animal for at least a twenty-four hour period, and during the first twenty-four hours of that period, at least seventy-five percent of the starch content of the rumen-retained portion of the fed feedstuff is digested.

Method for processing prolamin-containing feed for a ruminant animal to potentiate milk production or conception

An insertion device, generally used with an infusion set, including a needle being adapted for puncturing at one end and including at the opposite end a hub. The hub includes a handle part and a guard part that are capable of securing the needle through the use of locks. Locking structures are used to secure the insertion device in a position where the needle is covered in a locked position, avoiding unintended contact with the needle.

Insertion device

Growing community of inventors

Moorpark, CA, United States of America

Mark Dominis Holt