University of California

Dermbiont, Inc.

Mark De Souza

Christopher Phillips

Emma Taylor

Elizabeth Pilon-Smits

Norman Terry

Charles Rodney Greenaway Evans

Brendan Philip Brady

Ravi Kumar Pandrapragada

Karl Beutner

Vanessa Alexandra Cofré Urrutia

Provided herein are compositions comprising ruboxistaurin free base and its salts thereof and methods of use for treating conditions of the skin.

Compositions and formulations for use of a PK inhibitor for the prevention, treatment, and improvement of skin diseases, conditions, and disorders

The invention provides methods and compositions for trace element, particularly heavy metal phytoremediation, including plants which are genetically engineered to overexpress a sulfate assimilation pathway enzyme gene and thereby provide enhanced trace element accumulation. In various embodiments, the plants comprise the gene operably linked to a heterologous promoter, the plant is a member of the Brassicaceae family. In general, the methods comprise the steps of growing such plants in a medium such as soil or water comprising a trace element, under conditions wherein the gene is overexpressed, whereby the plant provides enhanced accumulation of the trace element, whereby the trace element content of the medium is decreased.

Trace element phytoremediation

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Berkeley, CA, United States of America

Mark De Souza