Gelman Sciences, Inc.

Mark D Heisler

Menahem A Kraus

Inessa Katsnelson

Menaham Kraus

Kariyawasam P Pemawansa

Diosie Velazques

Kanyawasam P Pemawansa

This invention relates to methods for gel electrophoresis, for sample transfer, for identifying a macromolecule, for blotting including dot blotting, and for colony hybridization, involving polyaldehyde activated microporous membranes.

Blotting methods using polyaldehyde activated membranes

Microporous membranes can be prepared which comprise a polymer which is a hydrophobic polymer in bulk form and which has an equilibrium water absorption from about 2% to about 4%, but is hydrophilic when precipitated as a membrane. The membranes are further characterized by high water flow rates at any given bubble point.

Filtration membranes and method of making the same

This invention relates to macromolecular transfers, gel electrophoresis, and blotting methods involving polyaldehyde activated microporous membranes.

An activated microporous membrane is provided, having aldehyde functional groups on its inner and outer surfaces. The aldehyde functionality on all surfaces provides for effective covalent bonding to the membrane by amine containing materials. The activated membrane can be made of a polysulfone/polyacrolein mixture or a polysulfone microporous membrane treated with a polyacrolein solution.

Polyaldehyde activated membranes

An activated microporous membrane is provided, having aldehyde functional groups on its inner and outer surfaces. The aldehyde functionally on all surfaces provides for effective covalent bonding to the membrane by amine containing materials. The activated membrane can be made of a polysulfone/polyacrolein mixture or a polysulfone microporous membrane treated with a polyacrolein solution.

Growing community of inventors

Saline, MI, United States of America

Mark D Heisler