Globus Medical, Inc.

Synergy Biomedical, LLC

Biomet Manufacturing Corporation

Biomet Sports Medicine, LLC

Global Medical Inc.

Mark D Borden

Anthony J Wirtel, Iii

Edwin Shors

Joseph M Hernandez

Kevin T Stone

Anthony Wirtel Iii

The present patent application is directed to compositions and shaped structures implantable into mammalian bodies, the compositions and shaped structures having localized bioactive surfaces.

Implantable bodies comprising a regional composite

Inflatable multi-chambered devices are provided for repairing or replacing spinal discs and distracting neighboring vertebral elements. Also included are cushioning devices that may be used in a joint replacement device cushioning system. Further included are kits and systems that include such devices, methods for making such devices, and methods of treating patients in need of such devices. Examples further include cosmetic augmentation and restoration devices.

Inflatable multi-chambered devices and methods of treatment using the same

Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same.

Porous and nonporous materials for tissue grafting and repair

A composite material for positioning in the anatomy to form a selected function therein. The composite may be resorbable over a selected period of time. The composite may allow for selected bone ingrowth as absorption of the composite occurs.

Continuous phase composite for musculoskeletal repair

An implantable interference screw for use in a soft tissue repair, the screw having a bioresorbable body comprising a plurality of interconnected pores, the body having an instrument interface in one end and a thread around an exterior of the body starting from distal end. The plurality of interconnected pores of the resorbable body are substantially filled with a bioresorbable polymer.

Continuous phase compositions for ACL repair

The present invention provides novel methods of forming mineralized gelatin carriers from bone. The present invention further provides mineralized gelatin carriers themselves; bone products that include such mineralized gelatin carriers including DBM bone products; and kits that include mineralized gelatin carriers formed from bone. The present invention further provides methods for making DBM bone products, wherein both the DBM and a mineralized gelatin carrier for the DBM are derived independently from a bone lot.

Bone graft materials derived from mineralized gelatin

The present invention is directed to implantable compositions comprising substantially spherical bioactive glass particles.

Compositions and their use in bone healing

Implants, such as interbody spacers, fusion devices and bone grafts, are provided having improved mechanical properties and/or degradation profiles. Such implants include a three-dimensional scaffold formed from particles, such as microspheres, which may in some embodiments be resorbable or biodegradable and which may have at least two different degradation rates. In some embodiments, the scaffold may be elastomeric. The three-dimensional scaffold may be for example, porous or semi-porous. Also provided are kits including such implants, and methods of producing and using the same.

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Foothill Ranch, CA, United States of America

Mark D Borden