Sharp Life Science (Eu) Limited

Mark Childs

Masahiro Adachi

Michael James Brownlow

Benjamin James Hadwen

Adrian Marc Simon Jacobs

Jason Roderick Hector

Alison Mary Skinner

A method of determining the result of an assay in a microfluidic device includes the steps of: dispensing a sample droplet onto a first portion of an electrode array of the microfluidic device; dispensing a reagent droplet onto a second portion of the electrode array of the microfluidic device; controlling actuation voltages applied to the electrode array to mix the sample droplet and the reagent droplet into a product droplet; sensing a dynamic property of the product droplet; and determining an assay of the sample droplet based on the sensed dynamic property. The dynamic property is a physical property of the product droplet that influences a transport property of the product droplet on the electrode array. Example dynamic properties of the product droplet include the moveable state, split-able state, and viscosity based on droplet properties. The method may be used to perform an amoebocyte lysate (LAL) assay.

Droplet microfluidic device and methods of sensing the result of an assay therein

Droplet microfluidic device and methods of sensing the results of an assay therein

Growing community of inventors

Formby, United Kingdom

Mark Childs