Nexeon Medsystems, Inc.

Gore Enterprise Holdings, Inc.

Boston Scientific Scimed, Inc.

Celonova Stent, Inc.

Nexeon Medical Systems, Inc.

Celonova Biosciences, Inc.

Baff LLC

W. L. Gore & Associates, Inc.

Biosensors International Group, Ltd.

Arteria Medical Science, Inc.

Paragon Intellectual Properties, LLC

Global Gene Therapies, Inc.

Cook Medical Technologies LLC

Boston Scientific Corporation

Mark C Bates

Michael Hogendijk

Kent C B Stalker

Andy Edward Denison

Juan C Parodi

Nicola A Pisano

Michael J Horzewski

Peter J D'Aquanni

Gerald Dorros

John D Whitfield

Jason Andrew Habeger

Edward H Cully

Barry Weitzner

Peter L Dayton

Ryan Boucher

Jeff Gray

David M Williams

Gaurav Rohatgi

Petrus Antonius Besselink

Douglas Melanson

Katharine Eckerline

Wei Li Fan

Michael Hogenduk

Shannon S Kenwood

Alex Broerman

Benjamin Peterson

Ryan P Boucher

Kent Cb Stalker

A medical device that comprises a rim defining a loop in a plane and defining a width measured perpendicular to the plane, at least one wire coupled to a distal end of the rim and extending proximally from the distal end out of the plane to a proximal end of the rim, the at least one wire having a cross-sectional dimension measured perpendicular to a longitudinal axis of the at least one wire, the cross-sectional dimension being smaller than the width of the rim, and a sheath configured to cover at least a portion of the rim and a portion of the at least one ware.

Device for tissue removal

Some embodiments relate to a catheter system having a changeable or adjustable working length. The catheter system can comprise a proximal end, a distal end, and a first axial lumen configured to receive a guidewire formed through at least a portion of the catheter body. A first opening can be formed through a portion of the catheter body and be in communication with the first lumen. The sheath can be rotatable, axially movable, or otherwise changeable from at least a first position to a second position, wherein the sheath can substantially cover the first opening in the catheter body in the first position, and can substantially expose the first opening in the catheter body in the second position.

Inventory sparing catheter system

A stent may include a connector having a first portion, a second portion, and a third portion positioned between the first and second portions. The connector may be configured to interconnect axially adjacent stent segments. The connector may be further configured such that the third portion severs in response to a threshold amount of axial force, axial foreshortening, and/or cyclic loading or fatigue, in order to predispose the severance of one or more pre-configured connectors in a controlled manner to minimize any potential harm to the surrounding vasculature of a patient.

Stent having at least one connecting member configured to controllably sever in vivo

Catheters for the removal of occlusions in a patient's vasculature. Exemplary catheters use a flexible distal end tube which is capable of coiling irregularly within the occlusion and securing it for removal.

Recanalization device

An expandable, bistable open cell design incorporates the following features: a first relatively stiff portion () having first and second ends and a first relatively flexible portion () connected to the first and second ends of the first relatively stiff portion, the first relatively stiff portion and the first relatively flexible portion substantially surrounding a first open area () of the stent structure; a second relatively stiff portion () having first and second ends and a second relatively flexible portion () connected to the first and second ends of the first relatively stiff portion, the first relatively stiff portion and the first relatively flexible portion substantially surrounding a second open area () of the stent structure; and an opening () formed through the first relatively stiff portion and the second relatively flexible portion such that the opening connects the first and second open areas, thereby creating first and second intermediate ends () of the first relatively stiff portion and first and second intermediate ends () of the second relatively flexible portion. The first intermediate end () of the relatively stiff portion is connected to the first intermediate end () of the relatively flexible portion so as to create a first inward apex (), the second intermediate end () of the relatively stiff portion is connected to the second intermediate end () of the relatively flexible portion so as to create a second inward apex (), and the stent structure is configured such that, in a collapsed configuration, the first inward apex () is in contact with the second inward apex () and, in an expanded configuration, the first inward apex is biased to move in a first circumferential direction and the second inward apex is biased to move in a second circumferential direction that is different than the first circumferential direction.

Expandable devices

Interventional catheters are disclosed for use in performing diagnostic and therapeutic procedures in vessels that are accessed retrograde to blood flow. The catheters include an elongated shaft slidably disposed within a sheath, a distal region having an end effector and a filter disposed proximal to the end effector to capture emboli liberated during the diagnostic or therapeutic procedure. The filter includes a plurality of struts that cooperate with an exterior surface of the catheter to define a reservoir to retain captured emboli, the reservoir configured so that advancement of the sheath contracts the filter without squeezing or dislodging captured emboli beyond a distal end of the filter.

Interventional catheter for retrograde use having embolic protection capability and methods of use

The present invention provides and apparatus and methods for emboli removal and stenting within the renal arteries having a catheter system having a distal occlusion element, a stent deployment section, and an emboli removal lumen. The occlusion element is disposed at a predetermined distance from the stent deployment section specific for use in the renal artery, and is constructed to reduce the potential for perforation or jailing during stent deployment. The apparatus further includes an array of radio-opaque markers disposed on the stent delivery catheter to facilitate accurate stent deployment within a renal artery.

Apparatus and methods for renal stenting

Methods and apparatus are provided for treating an injured or severed nerve pathway, wherein one or more microporous tubes are implanted into the nerve pathway to bridge the injured or severed region. A bioactive matrix including stem cells and nutrients is disposed within the microporous tube to facilitate growth of the stem cells and reestablishment of the sensory and motor conductive pathways through the injured or severed region. The microporous tube protects the bioactive matrix during development of the stem cells, and also retains the end regions in proper alignment during the nerve pathway regeneration.

Methods for treating an injured nerve pathway

Inventory sparing catheter systems and methods

Methods and apparatus are provided for delivering a bioactive agent in a needle track formed in a target tissue mass, following formation of the needle track, by avoiding impingement of the agent against target tissue at high velocity or by using capillary action to draw the bioactive agent out of the needle during needle withdrawal. The apparatus comprises a catheter and a needle disposed within the catheter and configured to be selectively extended into the tissue mass to a predetermined depth, while dispensing the agent simultaneously with retraction of the needle along the needle track. Alternatively, or in addition, the needle may be configured to create a tissue space surrounding a distal or lateral surface of the needle, into which the bioactive agent to be infused.

Systems and methods for atraumatic implantation of bio-active agents

Vascular prostheses and methods of use are provided, wherein the vascular prosthesis includes a plurality of bistable unit cells configured to form a helical structure. A visualization catheter also is provided for use ensuring accurate measurement of a lesion and ensuring delivery and placement of the vascular prosthesis.

Fracture-resistant helical stent incorporating bistable cells and methods of use

A dilatation catheter for delivering a therapeutic agent within a body lumen having a wall with a thickness is provided having a balloon having a flexible wall including a polymer with dispersed nanotubes and pores configured to close below a predefined pressure and to open at or above a predefined pressure. In some embodiments, an actuator is provided to controllably inflate the balloon with a fluid at a pressure sufficient to bring the flexible wall of the balloon into contact with at least a portion of the wall of the body lumen but below the predefined pressure, and to controllably increase the pressure of the fluid within the inflated balloon to at least the predefined pressure at a rate and with a force sufficient to deliver the therapeutic agent from the pores and through at least a portion of the thickness of the wall of the body lumen.

Nanotube-reinforced balloons for delivering therapeutic agents within or beyond the wall of blood vessels, and methods of making and using same

Growing community of inventors

Charleston, WV, United States of America

Mark C Bates