University of California

Other

The United States Government as Represented by the Department of Veterans Affairs

Mark B Ratcliffe

Kevin Edward Healy

Samuel Thomas Wall

Julius Guccione

Liang Ge

Alan Bao-Chan Dang

A method and system are presented for performing virtual surgery simulations. The computer system includes a processor and a memory. The method includes receiving user input from a user via a user interface. The user input includes input representing surgical operations or non-surgical invasive procedures. The method also includes processing the user input and utilizing the input to generate or modify a computational model. The method also includes running simulations using the computational model in accordance with the user input. After running the simulations, the method further includes determining results from the simulations. The results correspond to probable effects or outcomes of performing real life surgical operations or non-surgical invasive procedures corresponding to the user input. Last, the method includes presenting the results to the user via the user interface.

System and method for performing virtual surgery

The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineering applications, as a supporting matrix in the stabilization of an injured or defective myocardial wall in a patient comprising injecting a polymer network at a pre-selected site in the myocardial wall of the patient.

Methods and compositions for stabilizing the myocardium

The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium. For example, the present invention provides methods of stabilizing an injured or defective myocardial wall in a patient including forming a prosthetic in situ by injecting, at a pre-selected site in the myocardial wall of the patient, a polymer network including: a cross-linked polymer, the cross-linked polymer being a hydrogel; and a linear polymer, the polymer chains of which are entangled within the cross-linked polymer, wherein the linear polymer is not covalently bonded to the cross-linked polymer.

The present invention provides materials and methods that can serve as a prosthetic and/or, for tissue engineer applications, as a supporting matrix in the stabilization of the myocardium.

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Piedmont, CA, United States of America

Mark B Ratcliffe