Merck Sharp + Dohme Corp.

Mark Andrew Miller

Tessie Brown McNeely

Loren D Schultz

Rosemarie Kelly

Hongxia Fan

Mark D Yeager

The novel protein SA1789 fromis provided as well as nucleic acid and nucleic acid sequence homologues encoding this protein. Also provided is a composition, particularly avaccine, comprising SA1789 protein or a fragment or derivative thereof capable of generating an immune response that leads to the killing and clearance of

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The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 or a fragment thereof,AhpC-AhpF compositions, and uses of such polypeptides and compositions. SEQ ID NO: 1 has a full lengthAhpC sequence. A derivative of SEQ ID NO: 1 containing an amino His-tag and three additional carboxyl amino acids was found to produce a protective immune response against. 

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Wyndmoor, PA, United States of America

Mark Andrew Miller