The Texas A&M University System

Lawrence Livermore National Security, LLC

Shape Memory Medical, Inc.

Szafron, Jason M.

Muschenborn, Andrea D.

Wierzbicki, Mark A.

Nash, Landon

Maitland, Duncan

Landsman, Todd

Miller, Matthew W.

Mark A Wierzbicki

Duncan J Maitland

Landon D Nash

Todd L Landsman

Thomas S Wilson

Keith Hearon

Jennifer Nicole Rodriguez

Jason Szafron

Andrea D Muschenborn

Anthony J Boyle

Alan C Glowczwski

Matthew W Miller

Wonjun Hwang

Jason M Szafron

Todd Landsman

Duncan Maitland

Landon Nash

An embodiment includes a system comprising: a catheter; an optic fiber having a long axis and a short axis that is orthogonal to the long axis; first and second radiopaque elements coupled to the optic fiber; a first wire coupled to the optic fiber and extending from the first radiopaque element to the second radiopaque element; a fluid; wherein (a)(i) the first wire wraps at least partially around an exterior surface of the optic fiber; (a)(ii) an outer diameter of the first wire and an outer diameter of the optic fiber are collectively less than an inner diameter of the catheter, and (a)(iii) the first wire is configured to center the optic fiber within the catheter within a plane orthogonal to the long axis.

Heated endovascular catheter injection device

A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.

Biocompatible biomedical occlusion device

An embodiment includes a platform shape memory polymer system. Such an embodiment exhibits a blend of tunable, high performance mechanical attributes in combination with advanced processing capabilities and good biocompatibility. A post-polymerization crosslinking synthetic approach is employed that combines polyurethane and thiol-ene synthetic processes. Other embodiments are described herein.

Processable, tunable thiol-ene crosslinked polyurethane shape memory polymers

An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit.

Shape memory polymer vessel occlusion device

Processable, tunable thio-ene crosslinked polyurethane shape memory polymers

Growing community of inventors

College Station, TX, United States of America

Mark A Wierzbicki