Teledyne Scientific and Imaging, LLC

Mark A Peot

Warren M Grill

Mario Aguilar

Stephen Simons

Jiangying Zhou

Dennis Turner

Aaron T Hawkins

A flat optogenetic cuff interface (FOCI) is configured for functional optical stimulation of axons in a single fascicle of a peripheral nerve bundle in which the axons have been genetically modified to express light sensitive proteins for excitation or inhibition of the nerves. The FOCI is configured to gradually reshape the single fascicle to a final height between 0.2 mm and 0.5 mm by reorganizing the individual axons within the fascicle without reshaping (and damaging) the individual axons. The FOCI facilitates stimulation of axons over the entire cross-section of the reshaped fascicle within the power limitations for pulsed laser energy. An electrical interface may be included to sense nerve activity of either the stimulated axons to provide closed-loop feedback to control the optical sources or stimulated axons of a different modality to record the response. The FOCI may be used as an interface for prosthetic devices to restore lost sensory or motor function, to augment human sensor or motor performance or to modulate autonomic functions.

Flat optogenetic cuff interface (FOCI) for a single nerve fascicle of the peripheral nervous system

EEG-based acceleration of second language learning is accomplished by measuring via single-trial EEG a learner's cognitive response to the presentation (visual or auditory) of language learning materials and updating a user model of latent traits related to language-learning skills in accordance with the cognitive response. The user model is suitably updated with each trial, each trial being triggered by learner fixation on a portion of visual materials and/or a next phoneme in auditory materials. Additional discrimination may be achieved through the use of saccades or fixation duration features.

EEG-based acceleration of second language learning

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Chapel Hill, NC, United States of America

Mark A Peot