Covidien LP

Atrionix, Inc.

Medtronic, Inc.

Mitralign, Inc.

Flowmedica, Inc.

Advanced Cardiovascular Systems, Inc.

Other

Medtronic Cardiorhythm

Atrionx, Inc.

Edwards Lifesciences Corporation

Angiodynamics, Inc.

Astrionix

Mark A Maguire

Hillary K Huszar

Michael D Lesh

James Clayton Peacock, Iii

Edward L Carcamo

Paul A Spence

John O McWeeney

Shawn C Daniel

Alexander Arthur Lubinski

John W Gaiser

Alan K Schaer

Le Trong Le

Olivia P Metcalf

Madeline A Mannion

Thomas Pham

Walter Bruszewski

David S Utley

Edward I McNamara

Allen Jameson

Martin F O'Sullivan

Kevin Jude Taylor

Christopher L Bagley

Kevin C Ladd

Guillermo P Picazo

Hiroatsu Sugimoto

Steven D Cahalane

Aaron M Call

Aurelio Valencia

Donald S Baim

Ed McNamara

Richard Geoffrion

Jason Robinson

Joseph P Lane

Michel Haissaguerre

Hong Li

Samir R Patel

Harry Burt Goodson, Iv

Jeffrey M Elkins

Jeevan Maddur Shankarsetty

Huu Nguyen

Yogesh Kishor Vikharankar

Frank Nguyen

Kate E Cutuli

Inderjeet Singh Bhalla

Vijayaraghavan Srinivasan Chari

Neeraj Eswaradas

Narsing Sairaj Bheemarthi

Dylan S Reinsdorf

Francisco G Cosio

Michael D Dake

Veijo T Suorsa

Michael Peter Ross

Michael R Ross

Brian Tinkham

Richard J Morrill

Richard S Jaraczewski

Nitin P Matani

Michael Sansoucy

Lambert J Diettrich

Jeffrey T Sawyer

Larry W Shearon

Joseph M Karratt

Sebastian E Arevalo

Monika P Marciniak

Robert G Carruthers

Sergiy P Kanilo

Salim M Motiwala

Ali S Ghaderi

Benjamin J Pagliuso

Scott Bartfield

David H Hamilton

David J Karasek

Ananta Venkata Varaha Lakshmi Narasim Srinivasa Murthy Aravalli

Ananta Venkata Varaha Lakshmi Narasimha Srinivasa Murthy Aravalli

Ramiro L Reyes

Allen D Jameson

Alan K Shaer

James C Peacock

Alexander A Lubinski

Martin F O'sullivan

Kevin M Morris

William J Camisa

Michael Haissaguerre

A manometric catheter probe includes a flexible printed circuit, one or more pressure sensor assemblies coupled to the flexible printed circuit along a length of the flexible printed circuit, and a first flexible sleeve. Each pressure sensor assembly includes a body. The body includes a central cavity configured to receive the flexible printed circuit and an annular recess of the body. Each pressure sensor assembly further includes a microelectromechanical systems (MEMS) sensor disposed in the annular recess, an electrical connector configured to electrically couple the MEMS sensor and the flexible printed circuit, and a first flexible sleeve disposed over the annular recess of the body. The first flexible sleeve includes a fluid configured to communicate pressure to the MEMS sensor, and a second sleeve is disposed over the pressure sensor assembly.

Circumferentially sensing manometry systems and methods with catheter utilizing pressure sensitive mems

Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. A stent delivery system may include a tubular member configured to advance through an access site and a primary constrainment member configured to releasably couple the stent to the tubular member. The stent delivery system may further include a secondary constrainment member at least partially disposed around the primary constrainment member, the stent, and the tubular member. In some cases, the tubular member and the primary constrainment member may be configured to reposition the stent within the body lumen after removal of the secondary constrainment member such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the primary constrainment member, and the secondary constrainment member from the body lumen through the access site.

Apparatuses for stent delivery and positioning to cover an access site

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering the stent through an access site and deploying a distal portion of the stent from within an outer sheath. In some cases, the method may further include pushing a proximal portion of the stent from the outer sheath such that upon fully exiting the outer sheath, the proximal portion extends proximally to at least partially cover the access site with the stent. The system for delivering the stent into the body lumen may include a stent, a stent delivery apparatus, and an outer sheath. The system may further include an internal pusher configured to push a proximal portion of the stent from the outer sheath and axially compress the stent such that upon fully exiting the outer sheath, the proximal portion extends proximally to cover the access site.

Expandable stent delivery apparatus to cover an access site

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member front the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

Rotatable stent delivery apparatus to cover access site

Systems, devices and methods for securing tissue including the annulus of a mitral valve. The systems, devices and methods may employ catheter based techniques and devices to plicate tissue and perform an annuloplasty.

Tissue anchors, systems and methods, and devices

Methods, apparatuses and systems are described for administering a swallowable cell collection device to a patient. Methods include releasing a swallowable bundle of string of the cell collection device from a bundling apparatus, maintaining the string in a swallowable bundle while releasing the swallowable bundle from the bundling apparatus, and placing the swallowable bundle on the tongue of the patient. Methods also include constraining a retrieval string of the cell collection device in a swallowable bundle with a dissolvable band and placing the swallowable bundle on the tongue of the patient.

Designs and methods to facilitate swallowing of a tethered cell collection device

Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. The method may include delivering the stent through an access site in a wall of the body lumen. In some cases, the method may include repositioning the stent within the body lumen to at least partially cover the access site with the stent. The stent may be repositioned within the body lumen by retracting the stent towards the access site such that a proximal portion of the stent at least partially covers the access site. The stent may then expand within the body lumen. In some cases, the stent may expand within the body lumen by releasing a primary constrainment member from the stent by pulling the primary constrainment member in a proximal direction away from the stent.

Methods for stent delivery and positioning to cover an access site

Methods, apparatuses and systems are described for delivering a stent through an access hole of a body lumen and covering up the access hole after deploying the stent, Stents are described that include a stent body defining a body lumen contact surface area and a deployable member configured to deploy from the stent body and increase the body lumen contact surface area of the stent. Deployable members that hinge, unroll, extend, expand, and coaxially translate with respect to the stent body are described. A system for delivering a stent into a body lumen are described that may include a coverage member configured to at least partially cover the hole in the wall of the stent upon withdrawing a tubular member through the hole in the wall of the stent. Coverage members may include a self-sealing membrane, a flap valve, or a hinged valve.

Stent designs to cover catheter access site

Methods, apparatuses and systems for collecting cells from a body lumen are described. The system may include a cell collection device and a capsule configured to releasably retain the cell collection device. The cell collection device may comprise a plurality of distinct regions, each region comprising one or more material properties. In some instances, at least one material property of at least one distinct region differs from at least one material property of at least one other distinct region. The distinct regions may comprise different materials or may comprise the same material where at least one of the distinct regions is mechanically or chemically altered to yield the at least one differing material property.

Regions of varying physical properties in a compressible cell collection device

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Unfurling electrode devices

Methods, apparatuses and systems for collecting cells from a body lumen are described. A system may include a cell collection device comprising an abrasive material configured to collect cells from the body lumen by scraping a surface of the body lumen. The cell collection device may have a first end with a first diametric dimension and a second end with a second diametric dimension, wherein the second diametric dimension is larger than the first diametric dimension.

Tapered geometry in a compressible cell collection device

Methods, apparatuses and systems for collecting cells from a body lumen are described. The system may include a swallowable cell collection device comprising an abrasive and substantially non-absorbent material in a compressed configuration and configured to collect cells from the body lumen by scraping a surface of the body lumen. The system may further include one or more expansion elements coupled with the cell collection device configured to expand the cell collection device from the compressed configuration.

Use of expansion-force elements in a compressible cell collection device

Growing community of inventors

Hillsborough, CA, United States of America

Mark A Maguire