Other

Altiris Therapeutics, Inc.

Abbott Laboratories Corporation

Mark A Lockwood

Michael G Natchus

Florence Fevrier Wagner

Michael P Clark

Lawrence J Wilson

Yesim Altas Tahirovic

John Wiseman

Brandon C Doroh

Jason W Skudlarek

Tricia L Johnson

Gideon Shapiro

Michael J Dart

Youssef L Bennani

Yi-Yin Ku

William H Bunnelle

Sanjay R Chemburkar

Donald G Stein

Sou-Jen Chang

Dilinie P Fernando

Simona Jurczyk

Lei Wang

Paul Kardel

Jinhua Chen

Charles A Lockwood

Duane D Beyer

Lawrence Wilson

Christopher Macnevin

The invention provides compounds of Formula (I) and pharmaceutically acceptable salts, solvates, tautomers, stereoisomers, and/or esters thereof. These compounds, and pharmaceutical composition comprising such compounds are useful treating or preventing HIV infections, and in treating proliferative disorders such as inhibiting the metastasis of various cancers.

Chemokine receptor modulators

The present invention relates to the use of compounds of formula (I) for the treatment of epilepsy, bipolar disorder, psychiatric disorders, migraine, pain, or movement disorders, and to provide neuroprotection.

Spirocyclopropyl amides and acids and their therapeutic applications

Non-peptide somatostatin receptor ligands with conformationally restricted side chains exhibiting high binding affinity toward somatostatin receptors are provided. The compounds exhibit a high selectivity and act as agonists at human subtype 2 somatostatin receptors. The compounds are long acting for advantageous use as medicaments in peripheral diseases where somatostatinergic therapy is indicated. Furthermore, many of the compounds are lipophilic and are particularly useful for treating central nervous system and ophthalmic diseases where penetration of the blood brain and blood retinal barriers is required. It is a further object to describe the preferred stereoisomers of these somatostatin agonists and processes for their preparation. Further objects will become apparent from reading the following description.

Non-peptide somatostatin receptor ligands

An illumination device (10) for a phonograph record (18) has a housing (14) and bolts (22) for attaching the housing (14) to a phonograph tone arm (12). A battery (26) in the housing (14) and a contact switch (32) on the housing are connected to activate a timing circuit (28) for supplying current from the battery (26) to a light emitting diode (30). The light emitting diode (30) is positioned to illuminate an area around point (36) that stylus (20) contacts the record for a predetermined of time after the contact switch (32) is closed.

Phonograph record illumination device and system

Growing community of inventors

Alpharetta, GA, United States of America

Mark A Lockwood