Mesoscale Technologies, Llc.

Meso Scale Technology Llp

Mark A Billadeau

Eli N Glezer

Jonathan K Leland

George B Sigal

Mark T Martin

Larry Helms

Jeff D Debad

Bandele J Jeffrey-Coker

Joseph M Leginus

Koustubh A Phalnikar

Sriram Jambunathan

Jacob N Wohlstadter

Alan B Fischer

James L Wilbur

Michael Tsionsky

Liang-Hong Guo

Jon Leland

Svetlana Leytner

Ramin Darvari

Selen Altunata

Charles A Wijayawardhana

Alan Kishbaugh

Jeffery D Debad

Gisbert Spieles

Selen Stromgren

Nicholas Fox-Lyon

Paul Freese

Jambunathan Sriram

Jeffrey-Coker Bandele

Eli N Glazer

Eli Glazer

Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.

Assay cartridges and methods of using the same

The specification provides an assay electrode including a composite containing a matrix and a multiplicity of graphene particles dispersed therein.

Graphene-modified electrodes

The invention relates to improved electrochemiluminescence assay methods for phosphorylated peptides or proteins employing phospho-specific antibodies and buffer compositions that are substantially free of inorganic phosphate.

Kits suitable for use in electrochemiluminescence methods and methods of effecting a specific-binding non-wash assay

Assay buffer, compositions containing the same, and methods of using the same

Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

Multi-array, multi-specific electrochemiluminescence testing

Disclosed are methods for conducting assays of samples, such as whole blood, that may contain cells or other particulate matter. Also disclosed are systems, devices, equipment, kits and reagents for use in such methods. One advantage of certain disclosed methods and systems is the ability to rapidly measure the concentration of an analyte of interest in blood plasma from a whole blood sample without blood separation and hematocrit correction.

Methods and apparatuses for conducting assays

Growing community of inventors

Knoxville, MD, United States of America

Mark A Billadeau