Lts Lohmann Therapie-systeme Ag

Santhera Pharmaceuticals Ag

Marius Bauer

Christoph Schmitz

Marco Emgenbroich

Michael Linn

Markus Müller

Markus Muller

The invention relates to a transmucosal delivery system for idebenone, comprising an external phase, which contains at least one hydrophilic polymer, and an inner hydrophobic phase, which contains idebenone and at least one hydrophobic substance, wherein the inner hydrophobic phase is emulsified in the form of droplets in the external phase. The invention is characterized in that the inner hydrophobic phase is stabilized by at least one emulsifier in the external phase. The invention also relates to a method for producing the same and its use as a medicament.

Transmucosal delivery system for idebenone

The present application relates to a transdermal therapeutic system comprising a backing layer impermeable to active substances and a polymer matrix on one side of the backing layer impermeable to active substances, wherein the polymer matrix comprises at least one pharmaceutically active substance, at least one inherently non-self-adhesive polymer and at least one plasticizer, said polymer matrix being free of adhesive polymers. The invention further relates to a method of producing the transdermal therapeutic system and to the use thereof as a drug.

Transdermal therapeutic system on the basis of adhesive plasticizer-polymer matrices

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Andernach, Germany

Marius Bauer