Virginia Tech Intellectual Properties Inc

Marissa N Rylander

Rafael V Davalos

Christopher B Arena

John L Robertson

John H Rossmeisl

Christopher Rylander

Mehmet Alpaslan Kosoglu

Yong Woo Lee

Robert L Hood

David C Grant

The present invention relates to the field of optical imaging and therapeutics. More particularly, embodiments of the present invention provide minimally-invasive Fiberoptic Microneedle Devices (FMDs) for light-based therapeutics, which physically penetrate tissue and deliver light directly into the target area below the skin surface. Embodiments of the invention enable depth-selective and deep photothermal therapeutics and include methods of treating cancer, methods of re-shaping or removing adipose tissue, and methods of delivering drugs or co-delivering drugs and energy to selected tissue.

Fiber array for optical imaging and therapeutics

The present invention provides methods, devices, and systems for in vivo treatment of cell proliferative disorders. The invention can be used to treat solid tumors, such as brain tumors. The methods rely on non-thermal irreversible electroporation (IRE) to cause cell death in treated tumors. In embodiments, the methods comprise the use of high aspect ratio nanoparticles with or without modified surface chemistry.

Irreversible electroporation using nanoparticles

Growing community of inventors

Blacksburg, VA, United States of America

Marissa N Rylander