Vita-invest S.a.

Infinitec Activos, S.l.

Lacer, S.a.

Marisabel Mourelle Mancini

Juan Carlos Del Castillo Nieto

Elisabet De Ramon Amat

Francisco Pubill Coy

Lydia Cabeza Llorente

Joan Huguet Clotet

Jose Repolles Moliner

Juan Huguet Clotet

Ramona Galatola

José Repollés Moliner

Maria Elisa Alea Reyes

Juan Martínez Bonín

Magdalena Carceller Margeli

Ana Modolell Saladrigas

Luis Javier Cruz Ricondo

Maria Chalaux Freixa

Aimée Vasconcelos Pacheco

María Elisa Alea Reyes

Camila Folle

Microcapsules contain a peptide (I), and peptides (II) or (III) coupled to a PLGA-containing polymeric shell. The microcapsules can be used to enhance skin penetration of active ingredients encapsulated therein, particularly in the field of cosmetics. A process can be used for preparing the microcapsules, and compositions can contain said microcapsules. The microcapsules can be used as a transdermal delivery system for the active ingredients encapsulated therein.

Use of tetrapeptides and functionalised microcapsules as skin penetration carriers

A gold nanoparticles conjugated with palmitoyl pentapeptide-4 (Palm-L-Lys-L-Thr-L-Thr-L-Lys-L-Ser-OH), compositions comprising them, use thereof in cosmetic treatments, as well as methods for obtaining the nanoparticles.

Gold and palmitoyl pentapeptide-4 nanoparticles

The present invention relates to a compound of formula (I) and to compositions comprising said compound, as well as the use of said compound and/or said compositions to prevent fungal and/or bacterial growth.

Antimicrobial peptides and their application

The present invention relates to new 3-substituted 6-nitrooxy-hexahydrofuro[3,2-b]furane derivatives possessing a superior pharmacological activity in thrombosis and in coronary ischemia models.

Isosorbide nitrates

The present invention relates to stable S-nitrosothiols derivatives of formula (I) having vasodilating effect and which inhibit the aggregation of the platelets and which therefore are useful for the preparation of medicaments for treatment of NO related diseases. The invention also relates to a process for the synthesis of the compounds of formula (I).

Stable S-nitrosothiols, method of synthesis and use

The present invention refers to compounds of the general formula (I), to their possible pharmaceutically acceptable salts and tautomeric forms. The present invention also refers to a process for their production and to their use as antidiabetic and *hypoglycemic agents, alone or in combination with other antidiabetic agents, such as sulfonilureas or biguanides, as well as for the treatment of complications associated to the resistance to the insulin, such as hypertension, hyperuricemia or other cardiovascular, metabolic, endocrine conditions, or other conditions related with diabetes.

Thiazolidinedione derivatives as antidiabetic agents

New esters derived from (RR, SS)-3-(2-dimethylaminomethyl-1-hydroxycyclohexyl)phenyl 2-hydroxybenzoate, analog to Tramadol, a process for obtaining them and the use of these compounds for the production of a medicament with analgesic properties. These new products of general formula (I) exhibit an analgesic activity higher than that of tramadol.

Esters derived from (RR,SS)-2-hydroxybenzoate of 3-(2-dimethylaminomethyl-1-hydroxycyclohexyl)phenyl

New esters derived from substituted phenyl-cyclohexyl compounds, which are derived from Tramadol, process for obtaining them and their use for preparing a drug with analgesic properties. These new compounds of general formula (I) have a higher analgesic activity, a lower toxicity and a longer effective time period than Tramadol.

Growing community of inventors

Barcelona, Spain

Marisabel Mourelle Mancini