Laboratoires Expanscience

Marisa Meloni

Philippe Msika

Caroline Baudouin

Stéphanie Bredif

Stephanie Bredif

A skin model comprises keratinocytes capable of overexpressing filaggrin. A method for evaluating the in vitro activity of a formulation or of at least one active agent on the healing of nipple skin and/or on the reduction of nipple skin inflammation, by bringing said active agent or said formulation into contact with a skin model comprising keratinocytes overexpressing filaggrin and also comprising a lesion, and measuring the level of production of at least one biological marker chosen from lactate dehydrogenase (LDH), TNF&#x3b1;, filaggrin, TGF&#x3b2;1 and &#x3b2;1 integrin.

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Milan, Italy

Marisa Meloni