Research, Incorporated

Marion Dugdale

Ronald P Quintana

Andrew Lasslo

Randy W Johnson

This invention relates to certain N,N'-bis(nipecotyl)piperazines and their use as platelet aggregation inhibtory agents.

Platelet aggregation inhibitory agents and intermediate therefor

This invention relates to tetrahydroquinoline derivatives and their use for the inhibition of blood platelet aggregation.

Platelet aggregation inhibitory agents and intermediates therefor

A pharmaceutical composition in unit dosage form suitable for administration to an animal in need thereof comprising a pharmaceutically acceptable carrier and an amount sufficient to inhibit blood platelet aggregation of a compound selected from the group consisting of:

Platelet aggregation inhibitory agents

This invention relates to certain heterocyclic compounds which are useful as platelet inhibitory agents and intermediates for these compounds.

Various bis-nitrogen containing compounds exhibiting blood platelet aggregation inhibiting activity. One such compound being [substituted-N, N.sup.1 -Bis-(nipecotyl)]-piperazine.

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Memphis, TN, United States of America

Marion Dugdale