Schering Aktiengesellschaft

Schering Aktiengellschaft

Mario Kennecke

Alfred Weber

Rudolf Wiechert

Ulrich Eder

Klaus Nickisch

Helmut Dahl

Rudolf Muller

Rudolf Mueller

Gregor Haffer

Thomas Schmitz

Johannes Kurzidim

Heidi Hummel-Marquardt

Ernst Schottle

Henry Laurent

Gerhard Sauer

Gunter Neef

Klaus Annen

Hans Wendt

Detlef Wilke

Joachim-Friedrich Kapp

Uwe Klages

Hans-Jorg Vidic

Reinhold Wieske

Bernhard Krieger

Hermann Triem

Jean C Hilscher

Heidi Hummel-Maquardt

Ulf Tisltam

Gerhard Hempel

Alfred Popper

Rainer Phillippson

Process for the production of 17

Process for the production of arabinonucleosides

Process for the production of arabinonucleotides

A process for the production of dulcitol by fermentative reaction of lactose by galactokinase-negative mutants of genus Kluyveromyces is described, which is characterized in that

Process for the production of dulcitol from lactose

A process for the production of 4-androstene-3,17-dione and 1,4-androstadiene-3,17-dione of the general formula ##STR1## wherein . . . . . symbolizes a single bond or a double bond, characterized in that ergosterol ##STR2## is fermented with a culture of a microorganism strain capable of side-chain degradation of sterols.

Process for the production of 4-androstene-3,17-dione and

A process is claimed for the preparation of 4-androstene-3,17-dione and 1,4-androstadiene-3,17-dione of the general formula ##STR1## wherein  symbolizes a single bond or a double bond, characterized by fermenting .alpha.-sitosterol with a culture of a strain of microorganisms capable of side chain degradation of sterols.

Process for the preparation of 4-androstene-3,17-dione and

Process for the production of 4-pregnene-3,20-dione and its derivatives

Process for the production of ergoline derivatives

Fermentation process for the production of .beta.-carboline derivatives

6.alpha.,9.alpha.-difluoro-11.beta.,17.alpha.-dihydroxy-16.alpha.-methyl-4- pregnene-3,20-dione and its derivatives of general formula I ##STR1## wherein  symbolizes a single bond or a double bond, and

Process for production of

A process for preparing a 3-oxo-.DELTA..sup.1,4 -steroid comprises fermenting the corresponding 3-oxo-.DELTA..sup.4 -steroid, saturated in the 1,2-position, witih a living culture of Arthrobacter simplex in the presence of 0.04 g to 0.12 g of cobalt(II) ions per liter of culture broth.

Preparation of 3-oxo-.DELTA..sup.1,4 -steroids

A process for the extraction of aromatic (e.g., phenyl-containing) amino acids from an aqueous phase (solution) containing them, comprising combining the aqueous phase with a tenside of the formula

Process for the extraction of amino acids from an aqueous phase

A process for preparing 11.beta.,21-dihydroxy-2'-methyl-5'.beta.H-1,4-pregnadieno(16,17-d)-oxazole -3,20-dione, comprises fermenting 11.beta.,21-dihydroxy-2'-methyl-5'.beta.H-4-pregneno (16,17-d)-oxazole-3,20-dione with a living culture of Arthrobacter simplex.

Process for the preparation of

Steroids of the formula ##STR1## wherein represents a single or double bond,

Novel steroids of the pregnane series, substituted in the 17-position,

In a process for preparing 21-hydroxy-20-methylpregnane derivatives by fermenting a zoosterol or a phytosterol with a culture of Mycobacterium spec. NRRL B-3683 or NRRL B-3805 or a variant or mutant thereof,

Process for the preparation of 21-hydroxy-20-methylpregnane derivatives

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Berlin, Germany

Mario Kennecke