Perkinelmer Health Sciences, Inc.

The Perkin-elmer Corporation

Mario Carozza

Avinash Dalmia

Keith Ferrara

David J Eaton

Donald L Groeschner

Michael J Rafa

John McCaffrey

Andrew P Bajorinas

Gerard T Paul

J Fenton Williams

Steven L Paul

Mark W Stoltze

Robert F Barnes

Keith S Ferrara

A method and system of aligning a probe to wells includes holding the probe at one potential and holding the wells at a different potential, moving the probe to an estimated center position above a selected well, lowering the probe into the selected target well, moving the probe in positive and negative directions along first and second axial dimensions until changes in potential are detected at the probe to indicate electrical contact between the probe and the selected well, and calculating a center location of the selected well along the first and second axial dimensions as mid-points between the points of contact for the respective axial dimensions. The method and system further include lowering the probe into contact with a floor of the selected well and calculating a center location along a third axial dimension as a predetermined distance above the position of the probe. The method and system determine center locations for other wells based on known spacing between wells and the calculated center locations of one or more selected wells.

System and auto-alignment method for determining position using a discrete contact probe

The invention relates to an electrochemical sensor and method for providing the sensor having an insulator, an electrode deposited on the insulator, an electrolytic material in contact with the electrode for providing an electrical connection, and a cooling and heating element in contact with the insulator and spaced apart from the electrode for adjusting a temperature of the sensor.

Method and apparatus for providing an electrochemical sensor at an elevated temperature

A spectrometric instrument passes flashing light through a sample and has a linear detector operated by the computer to integrate signals for an established number of flashes to obtain an integrated unit of the signal data, from which spectral information is displayed on a monitor. Over a full spectral range, the established number is determined as that which effects a highest peak height proximately below a preselected maximum, and light source voltage is adjusted to bring the peak height closer to the maximum. For a narrower spectral range, an operating number of flashes for a unit is increased above the established number to accommodate a lower highest peak in the range. Wavelength calibration uses peaks in the light source. Corrections are made for stray light and non-linearity of detector response. Calculation of auxiliary information derived from input of auxiliary data through a touch screen is displayed on the monitor.

Computer operated spectrometric instrument and associated calculator

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Danbury, CT, United States of America

Mario Carozza