Meiji Seika Pharma Co., Ltd.

The Kitasato Institute

Meiji Seika Kaisha, Ltd.

The Kitasato Institute (a School Juridical Person)

Mitsui Chemicals Crop & Life Solutions, Inc.

Mariko Tsuchida

Kazuhiko Oyama

Kimihiko Goto

Hiroshi Tomoda

Ryo Horikoshi

Toshiaki Sunazuka

Masaaki Mitomi

Satoshi Omura

Kentaro Yamamoto

Hiroyuki Anzai

An isolated novel polynucleotide comprising a nucleotide sequence encoding at least one polypeptide involved in biosynthesis of pyripyropene A, a recombinant vector comprising the polynucleotide and a transformant comprising the polynucleotide are disclosed. By the present invention, a pyripyropene A biosynthetic gene useful for production of a novel pyripyropene analog, improvement of productivity of a pyripyropene A-producing bacterium, production of an insecticidal agent for microorganisms, creation of a plant resistant to insect pests or the like are provided.

Pyripyropene a biosynthetic gene

There is provided a method for culturing a microorganism in which a particular polynucleotide or a recombinant vector comprising it/them is introduced with an intermediate compound necessary for biosynthesis of pyripyropene A. The method of the present invention allows for the production of pyripyropene.

Method for producing pyripyropene

Disclosed is a composition for use as a pest control agent, comprising a compound represented by formula (I) or an agriculturally and horticulturally acceptable salt thereof as active ingredient and an agriculturally and horticulturally acceptable carrier: 

Pest control agents

There is provided a pest control agent comprising a compound represented by formula (I) as active ingredient. 

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Tokyo-to, Japan

Mariko Tsuchida