Mect Corporation

Mariko Ishii

Takayuki Ishii

Mamoru Sugimoto

Kenkichi Tomita

Makiko Kasano

Tae Yasunaga

Tomoya Ogawa

Masaaki Numata

Makoto Tanaka

Isao Suda

Nobuyuki Kibushi

Ryoichi Osawa

Naokazu Sugiyama

Takeshi Miyata

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts, thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Method for modulating the immune system

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Methods for inhibiting the chemotaxis of neutrophils

Anti-inflammatory agent

A preparation is useful for treating renal disease, such as nephritis and especially nephrosis (nephrotic syndrome), which comprises an effective amount of N-acetylneuraminic acid shown by the formula ##STR1## wherein, when n is 1, Z represents hydrogens, lithium, potassium, sodium, ammonium or organic ammonium, and when n is 2, Z represents calcium, barium or magnesium, and a pharmacologically acceptable carrier.

Preparation for treating renal disease

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Tokyo, Japan

Mariko Ishii