Kao Corporation

Kanebo, Limited

Mariko Hara

Shintaro Inoue

Takeshi Ikemoto

Hiroko Nakatsugawa

Shunsuke Yamazaki

Tomohiro Yokota

Shinichiro Nishimura

Masahiro Yoshida

Kyoko Fukunaga

Rie Uematsu

Fumio Nakajima

A skin cosmetic composition comprising the compound represented by the following formula (1): wherein Ris hydrogen and Ris hydrogen or glucose residue.

Dihydroxyphenyl compounds and glucoside compounds thereof

Galactosylceramide analogues represented by the following formula (1) or (2). (wherein X and Y each represent S or O, Rand Reach represent an alkyl group or an alkenyl group each having 9 to 35 carbon atoms. Rrepresents an alkyl group or an alkenyl group each having 2 to 30 carbon atoms.) It is provided a &#x3b2;-glucocerebrosidase activator which is easily available, and external skin preparations and a method of activating &#x3b2;-glucocerebrosidase, in which improvement in formation of horny layer transmission barrier is expected by activating &#x3b2;-glucocerebrosidase so that an improved effect in rough skin is also expected.

Galactosylceramide analogs, and &#x3b2;-glucocerebrosidase activators, external skin preparations and method of activating &#x3b2;-glucocerebrosidase using the analogs

The present invention is a compound represented by the following formula (1) or (2):where one of Rand Ris hydrogen and the other one is hydrogen or glucose residue. The compound is effective for reforming obese constitution, suppressing or preventing obesity. It is also effective for skin whitening.

Growing community of inventors

San Francisco, CA, United States of America

Mariko Hara