Eli Lilly and Company

Marie T Anderson

Karl H Michel

LaVerne D Boeck

Gladys M Clem

Charles L Hershberger

Thomas H Sands

David G Maskalick

New glycopeptide antibiotic CUC/CSV which has the formula: ##STR1## wherein R is L-ristosaminyl;

Glycopeptide antibiotic CUC/CSV and process for its production

There is disclosed herein a process for the purification of glucagon from a glucagon salt cake containing pancreas gland-sourced glucagon, which comprises

Process for recovering glucagon from pancreas glands

New glycopeptide antibiotics of the formula: ##STR1## wherein W is the remaining portion of a glycopeptide antibiotic selected from actaplanin factors B.sub.1, B.sub.2, B.sub.3, C.sub.1, C.sub.2, C.sub.3, D.sub.1, D.sub.2, E.sub.1, G, K, L, M, N, O and actaplanin .psi.aglycone, and salts thereof, particularly the pharmaceutically acceptable salts, are useful new antibiotics are active against gram-positive bacteria and increase feed-efficiency utilization and enhance milk production in ruminants.

Glycopeptide bioconversion products

New A52688 factors A, C, D, E, F, G, H, J and K which have the common general formula: ##STR1## are antibacterial and antineoplastic agents. Methods of preparing the antibiotics by culturing a strain of Mycoleptodiscus terrestris are provided.

Growing community of inventors

Indianapolis, IN, United States of America

Marie T Anderson