Bcm Developement Inc.

Marie-Josee Perron

Michel Page

Taxanes are purified by chromatographic separation using a phenylalkyl chromatographic resin, wherein the alkyl portion of the phenylalkyl is a C.sub.4 -C.sub.10 moiety. Taxanes such as paclitaxel, 10-deacetyltaxol, 7-epi-taxol, cephalomannine, baccatin III, baccatin V, 7-epi-DAB, 10-deactylbaccatin III ('DAB') and 9-dihydro-13-acetylbaccatin III ('DHB') and others may be purified. In accordance with the invention, taxanes are separated from each other and from other impurities common to crude taxane samples.

Growing community of inventors

Sainte-Foy, Canada

Marie-Josee Perron