Aventis Pharma S.a.

Rhone-Poulenc Rorer S.a.

Regeneron Pharmaceuticals, Inc.

Sanofi

Marie-Christine Bissery

Eric Steven Furfine

Jesse M Cedarbaum

Jocelyn Holash

Claudia Fromond

Patricia Vrignaud

Marielle Chiron-Blondel

Pascale Lejeune

Brigitte Demers

Joel Vacus

Thierry Verrecchia

Jean-Francois Dedieu

Clive Brealey

Simon Roberts

Alain Renard

Michel Laborie

Akbar Khan

This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations.

Antitumor combinations containing a VEGF-inhibiting agent and 5FU or a derivative thereof

Antitumor combinations comprising a taxane and at least one epidophllotoxin for treating neoplastic diseases are described.

Antitumor combinations containing taxane derivatives and epidophyllotoxins

Antitumor combinations comprising a taxane and at least one antimetabolite for treating neoplastic diseases are described.

Antitumour combinations containing taxotere and 5-fluorouracil

Antitumor combinations comprising a taxane and at least one antibiotic for treating neoplastic diseases are described.

Method of treating cancer with docetaxel and doxorubicin

Antitumor combinations comprising a taxane and at least one therapeutically useful substance for treating neoplastic diseases are described.

Method of treating leukemia with docetaxel and vinca alkaloids

This invention relates to therapeutic combinations comprising VEGF Trap and a stilbene derivative, and to methods for treatment of cancer comprising administration of such combinations.

Combination comprising combretastatin and anticancer agents

The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of an alkylating agent such as a platin derivative, and methods of using such therapeutic associations.

Composition comprising camptothecin or a comptothecin derivative and a platin derivative for the treatment of cancer

An antitumor combination comprising a stilbene derivative and an anticancer compound selected from the group consisting of taxanes, alkylating agents, antimetabolites, vinca alkaloids, platinum compounds, epidophylloptoxins, and antibiotics as the active ingredients is provided. Methods of using these pharmaceutical preparations for the treatment of solid carcinomas and the like are also provided.

Therapeutic pharmaceutical compositions comprising a pyrimidine derivative in combination with camptothecin or a camptothecin derivative for the treatment of cancer are described. In one embodiment, the pyrimidine derivative is capecitabine and the camptothecin derivative is CPT-11.

Composition and method comprising CPT-11 and a pyrimidine derivative for the treatment of cancer

A pharmaceutical combination for the treatment of cancers containing a stilbene derivative and a camptothecin is described.

Combination comprising camptothecin and a stilbene derivative for the treatment of cancer

The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of an alkylating agent, such as melphalan, dacarbazine, or cyclophosphamide, and methods of using such therapeutic associations.

Composition comprising camptothecin or a camptothecin derivative and an alkylating agent for the treatment of cancer

Composition comprising camptothecin or a camptothecin derivative and a platin derivative for the treatment of cancer

Composition comprising camptothecin and a pyrimidine derivative for the treatment of cancer

A pharmaceutical composition comprised of acetocyclopropyl taxotere or a derivatve thereof, and at least one of an alkylating agent, an antimetabolite, a spindle poison, an epidophyllotoxin, an antibiotic, an enzyme, a topoisomerase inhibitor, a platinum coordination complex, a biological response modifier or a growth factor inhibitor is described.

Antitumor compositions containing taxane derivatives

The present invention relates to a new pharmaceutical form of taxoid derivatives, and more particularly to the oral administration of a taxoid bearing two alkoxy groups in position 7 and 10.

Growing community of inventors

Vitry sur Seine, France

Marie-Christine Bissery