Council of Scientific and Industrial Research

Mariappanadar Vairamani

Pushpito Kumar Ghosh

Anil Srivastava

Brahm Shanker Srivastava

Ranjana Srivastava

Bhupendra Dhanvantrai Shethia

Jayant Batukral Pandya

Vinita Chaturvedi

Meena Rajnikant Rathod

Prakash Jagivanbhal Dodia

The present invention relates to enhancement of anti-tubercular activity of active fraction isolated from. The invention also discloses the non-toxic nature of the fraction and positively identifies Sucrose as its main constituent. Pure Sucrose is shown to have no anti-tubercular activity indicating thereby that activity of the fraction resides in one or more of the minor constituents. The minor constituents are shown to be relatively low molecular weight entities and a chromatographic technique is disclosed for separating them from the bulk sucrose to probe their activities and structures in detail, as also the possibility of their synthesis if the leads thrown up are novel.

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Andhra Pradesh, India

Mariappanadar Vairamani