Socpra Sciences Et Genie S.e.c.

Marianne Allard

Pierre Lacasse

Christian Lebeau Jacob

Brian Geoffrey Talbot

Daniel Scholl

Moussa Sory Diarra

François Malouin

Céline Ster

Eric Marsault

Jerome Mulhbacher

Daniel Lafontaine

Celine Ster

Jérôme Mulhbacher

Moussa S Diarra

Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0029, based on the gene nomenclature from theCOL (SACOL) genome.

Bacterial vaccine components and uses thereof

Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0442, based on the gene nomenclature from theaureus COL (SACOL) genome.

Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0029, SACOL0264, SACOL0442, SACOL0718, SACOL0720, SACOL1353, SACOL1416, SACOL1611, SACOL1944, SACOL2144, SACOL2365 or SACOL2599, based on the gene nomenclature from theCOL (SACOL) genome.

The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.

Guanine riboswitch binding compounds and their use as antibiotics

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Sherbrooke, Canada

Marianne Allard