Janssen Pharmaceutica Nv

Mariane Van Wambeke

Nico Boon

Willy Verstraete

Wim De Windt

Silver nanoparticles associated with 20 to 80% by weight of a biocomponent of the genus, said silver nanoparticles having a ratio of the average particle size to the specific surface area (BET) of from 0.015 to 0.15 nm/m/g; a method for producing silver nanoparticles, comprising the step of incubating bacteria of the genuswith an aqueous solution comprising at least 4 mM of a silver salt in the presence of ammonia and an alkali metal hydroxide until a biomass of bacteria containing Agsilver nanoparticles is formed; and optionally a further step of extracting said Agsilver nanoparticles from said biomass by means of concentrated alkali metal hydroxide or concentrated inorganic acid or enzymes; an anti-microbial composition comprising an effective amount of said silver nanoparticles; use of said silver nanoparticles for the manufacturing of an article or a composition with anti-microbial activity; a method for manufacturing an article or a composition with anti-microbial activity, comprising dispersing or impregnating said silver nanoparticles into said article or composition; and an article with anti-microbial property having said silver nanoparticles dispersed therein.

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Kluisbergen, Belgium

Mariane Van Wambeke