Itm Isotopen Technologien Munchen Ag

Scv Gmbh

Marian Meckel

Konstantin Zhernosekov

Mark Harfensteller

Jussi Jernström

Yury Totskiy

Frank Rösch

Jussi Jernstrom

AGe/Ga generator for a continuous production of aGa daughter nuclide, wherein theGe parent nuclide thereof is specifically adsorbed to an inorganic support material and wherein saidGe parent nuclide continuously decays toGa by electron capture at a half-life of 270.82 d, wherein the inorganic support material is at least one oxide of a metal being selected from the group consisting of: Vanadium, Niobium and Tantalum. The use of at least one oxide of a metal being selected from the group consisting of: Vanadium, Niobium and Tantalum as an inorganic support material for the manufacture of aGe/Ga generator for pharmaceutical purposes. With the inorganic support material of the present invention, it is possible to loadGe/Ga generators with up to 8000 MBq ofGe (corresponding to 80 &#x3bc;g Germanium).

68Ge/68Ga generator

The invention relates to a compound V for complexing metallic isotopes, comprising a chelator X and one or more targeting vectors conjugated with the chelator X, said targeting vectors having the structure -L-R-L-R-L-R, wherein Rcontains a bisphosphonate. A pharmaceutical consists of the compound V and a metallic isotope which is complexed with compound V. 

Conjugated bisphosphonates for the diagnosis and therapy of bone diseases

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Munich, Germany

Marian Meckel