Medtronic, Inc.

Medtronic Xomed, Inc.

Maria Nieves Gonzalez

Edze Jan Tijsma

Erica M TenBroek

Nancy Schaffhausen

Matthew Franco Myntti

Brian J Vaccaro

Erica M Tenbroek

Matthew F Myntti

Bodily tissue and structures may be protected using a fluid layer containing a mixture of chitosan and oxidized polysaccharide. The mixture forms a protective gel layer via in situ crosslinking. Compared to crosslinking using a low molecular weight aldehyde such as glutaraldehyde or genipin, oxidized polysaccharides appear to provide faster gelation while avoiding the use of potentially less bioacceptable low molecular weight aldehydes.

Protective gel based on chitosan and oxidized polysaccharide

Method for treating the ear, nose, sinus or throat

Body tissue and structures may be protected using a fluid containing a mixture of partially crosslinked polysaccharide and a further crosslinker. The mixture desirably is sprayable, forms a fluid protective layer via in situ crosslinking, desirably does not drip or run from a treatment site, and may avoid the use of more rapidly curing but potentially less bioacceptable crosslinkers at the treatment site.

Chitosan-containing protective composition

Growing community of inventors

Alcorcon, Spain

Maria Nieves Gonzalez