National Research Council of Canada

Illinois Tool Works Inc.

Tissue Growth Technologies Corporation

Maria Moreno

Danica Stanimirovic

Philippe Levesque

Jacob M Thibodeau

Traian Sulea

Yves Durocher

Mehdi Arbabi-Ghahroudi

Anne Marcil

Abedelnasser Abulrob

Balu Chakravarthy

Marzia Martina

Umberto Banderali

Jacob Thibodeau

The present disclosure concerns antibodies specific for the Na v.7 polypeptides which are capable of antagonizing the biological activity of the Na v.7 polypeptide. The anti-Na v.7 antibodies can be used for alleviating the symptoms of pain and/or for treating or alleviating the symptoms of an hyperproliferative disease. The presence disclosure also concerns immunogens and methods for making antibodies, such as the anti-Na v.7 antibodies, comprising a single-domain antibody.

Antibodies and antibody fragments against HNAV1.7 channel and their use in pain and cancer indications

The invention relates to antibodies or fragments thereof specific for insulin-like growth factor binding protein-7 (IGFBP7). A method of raising anti-IGFBP7 single domain antibodies is also disclosed and specific antibody clones are described, along with their binding characteristics. The anti-IGFBP7 antibodies may be useful as diagnostic tools for detecting neoplastic diseases involving tumor angiogenesis, and a variety of other angiogenesis associated diseases.

Formulations targeting IGFBP7 for diagnosis and therapy of cancer

An apparatus and method is described for seeding cells on a sample or specimen. The cells may be selectively and locally seeded on an upper and lower surface of a planar sample or specimen or on either or both of an interior luminal surface and exterior surface of a hollow sample or specimen. The apparatus includes a chamber suitable for cell seeding, cell growth, and cell conditioning.

Rotating cell seeding module

Cell seeding module

Growing community of inventors

Ottawa, Canada

Maria Moreno