Emisphere Technologies, Inc.

Maria Isabel Gomez-Orellana

Parshuram Rath

Andrea Leone-Bay

David Gschneidner

Destardi Moye-Sherman

Steven Minh Dinh

Pingwah Tang

Stephen V Pusztay

Jianfeng Song

John J Weidner

Huaizhen Wang

Edmund A Vuocolo

Steven c/o Emisphere Technologies Inc Dinh

Huaizhen c/o Emisphere Technologies Inc Wang

The present invention provides a composition (e.g., a pharmaceutical composition) comprising at least one delivery agent compound and at least one of peptide YY (PYY) and a PYY agonist. Preferably, the composition includes a therapeutically effective amount of peptide YY or the PYY agonist and the delivery agent compound. The composition of the present invention facilitates the delivery of PYY, a PYY agonist, or a mixture thereof and increases its bioavailability compared to administration without the delivery agent compound. PPY and PYY agonists possess activity as agents to reduce nutrient availability, including reduction of food intake.

Compositions for delivering peptide YY and PYY agonists

The present invention provides aryl ketone compounds and compositions containing them which facilitate the delivery of active agents. The aryl ketone compounds have the formula or a salt thereof, where n=1 to 9, and Rto Rare independently hydrogen, Cto Calkyl, Cto Calkoxy, Cto Calkenyl, halogen, hydroxyl, &#x2014;NH&#x2014;C(O)&#x2014;CH, or &#x2014;O&#x2014;CH.

Aryl ketone compounds and compositions for delivering active agents

Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.

Compounds and compositions for delivering active agents

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New Rochelle, NY, United States of America

Maria Isabel Gomez-Orellana