Brainlab Ag

Maria Inmaculada Rodriguez-Ponce

Raghu Raghavan

Martin Lee Brady

Stephan Mittermeyer

The invention relates a method and an apparatus of predicting or planning a temperature distribution () in a body. The method comprises the steps of: a) obtaining a model of the body () related to a temperature transport mechanism or temperature distribution () in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature () or heat distribution in at least a part of the body using the model of the body ().

Method and apparatus for estimating temperature in a body

A method for identifying target regions in a tissue for local drug delivery, where functional and/or structural anatomical data such as edema and/or resection cavity is captured by an imaging system, and where the anatomical data is evaluated by segmentation techniques such as region-growing-based methods with computer assistance to determine a margin around a resection cavity and/or the volume of edema, the margin and/or the volume of edema being the target tissue for local drug delivery.

Margin determination

The present invention relates to compensating for brain shift in catheter trajectory planning. First brain shift information is determined from an initial brain image dataset, an initial planning dataset, a patient orientation dataset, and first burr hole dataset. The brain image dataset is updated based on the first brain shift information and a trajectory of a first catheter is updated based on the updated brain image dataset. For a subsequent catheter placement, subsequent brain shift information is determined based on the updated brain image dataset, the patient orientation dataset, and a subsequent burr hole dataset. The brain image dataset is updated again based on the subsequent brain shift information. The re-updated brain image dataset is utilized to update trajectories of the subsequent catheter as well as any preceding catheters.

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Munich, Germany

Maria Inmaculada Rodriguez-Ponce