Cellmid Limited

Advangen International Pty Ltd

Maria Halasz

Darren Jones

Sadatoshi Sakuma

Nico Mertens

Phillip Cunnah

Sadatosi Sakuma

Takeo Matsumoto

Koichi Yamauchi

Masakuni Yamamoto

Masato Namekata

Darren Ross Jones

The present disclosure is directed to isolated or recombinant proteins, such as antibodies, which bind to, and inhibit or reduce the function of, midkine (MK) and their use as therapeutic and/or diagnostic agents for midkine-related disorders. The present disclosure is also related to nucleic acid sequences which encode said proteins and their expression in recombinant host cells. In particular, the present disclosure is directed towards humanized antibodies derived from murine antibody IP14 which specifically bind to human MK.

Midkine antibody

The present disclosure relates to isolated or recombinant proteins, such as antibodies, which inhibit or reduce the function of midkine (hereinafter, referred to as 'MK') for use in the treatment or prevention of midkine-related disorders.

Antibody recognizing N-domain of midkine

The present application relates to use of a Midkine family protein for growing hair on a mammal, or in the manufacture of a medicament for growing hair on a mammal, especially for treatment or prevention of different forms of alopecia.

Method of treatment or prevention of hair loss or for the enhancement of hair growth

Growing community of inventors

Sydney, Australia

Maria Halasz