Sorin Biomedica Cardio S.p.a.

Sorin Biomedica Cardio, S.r.l.

Sorin Biomedica S.p.a.

Cid S.p.a.

Sorin Biomedics S.p.a.

Cid S.r.l.

Alvimedica Tibbi Ürünler Sanayi Ve Dis Ticaret A.s

Maria Curcio

Franco Vallana

Giovanni Rolando

Paolo Gaschino

Benito Chinaglia

Stefano Rinaldi

Pietro Arru

Andrea Grignani

Enrico Pasquino

Gioacchino Bona

Laura Ghione

Carla Stacchino

Leopoldo Della Ciana

Gioachino Bona

Vincenzo Cassolaro

Ilaria Zambaldi

Anilla Massaglia

Giuliana Bernacca

Daniela Gramaglia

Stefano Rinalki

Piero Arru

Davide Gastaldin

Composition for delivery of at least one active principle at the implantation site of an implant device, including:

Composition for active principles delivery containing a fatty acid excipient

A process for depositing an active substance on selected regions of the surface of a stent, comprising: (i) providing the active substance in at least one form selected from the group consisting of a powder and a paste; and (ii) depositing the active substance on the selected regions of the surface of the stent. Preferably, the active substance comprises or consists essentially of FK506, such as FK506 in the form of a powder with a grain size smaller than 15 micron or a paste with a base of FK506 with a viscosity not lower than 100,000 to 120,000 cps.

Process for producing stents and corresponding stents

A stent has surface sculpturing, preferably on its outer surface only, having, for example, microspheres, having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent to the blood vessel wall.

Process for producing a stent for angioplasty

Method of making a medicated stent

A stent for use at an implant site in a vessel having recesses containing one or more active agents. The stent is a tubular body having a plurality of sinusoidal shaped annular elements and connection elements. The recesses are formed so as to leave substantially unaltered the bending moments of these elements. The recesses may be continuous or discontinuous and may be distributed uniformly or nonuniformly.

Angioplasty stents

An actuating device for a catheter comprising at least one first part and one second part, which are able to more relative to each other, the actuating device comprising: (i) a slide which can be connected to one of said first part and said second part of the catheter; (ii) a slider, which can be actuated for moving said slide and moving said first part and said second part relative to each other; and (iii) a speed-change mechanism, which is set between said slider and said slide.

Actuating device for catheters

The stent for angioplasty has a body in the form of a generally tubular casing capable of being dilated in use from a radially-contracted position to a radially-expanded position. The body includes a support structure made from a first material capable of withstanding this dilation without losing its structural integrity. A structure made from a second material which has been rendered radioactive following the exposure of the stent itself to a neutron flux is associated with at least a portion of the carrying structure.

Stent for angioplasty and a production process therefor

The stent ( ) has surface sculpturing, preferably on its outer surface ( ) only, constituted, for example, by microspheres ( ), having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent ( ) to the blood vessel wall.

Stent for angioplasty and associated production process

A device, method, and kit for conveying a radioactive agent to a site of stenosis. The device includes a body portion to be disposed about the surface of a stent. The device comprises a radioactive agent. The device is capable of expanding, thus following the deployment movement of the stent, and is used to counter restenosis.

Device for conveying radioactive agents on angioplasty stents, respective method and kit

A stent structure includes a stent and one or more fibers disposed on the stent, the fiber adapted to provide a therapeutic agent. Nuclei containing therapeutic agents that impede restenosis may be included within the fiber or within separate particles that are contained within hollow core fibers. The fibers and the particles may be bioerodible. A permeable, biocompatible sheath may be interposed between the stent and the fiber. A kit including a stent, a fiber, and a delivery catheter is also described.

Angioplasty stent adapted to counter restenosis respective kit and components

This invention is a stent having a substantially tubular body defining a longitudinal axis comprising first and second adjacent annular segments, each segment defining a substantially sinusoidal shape having a plurality of peaks and valleys, the peaks of the first segment extending toward the second segment and being aligned longitudinally with the valleys of the second segment. The stent has a plurality of bridge elements having a U-shaped portion between first and second connector arms, the first connector arm of one bridge element being connected between a first peak and a first valley of the first segment and the second connector arm being connected between a first peak and a first valley of the second segment in a manner such that the U-shaped portion extends in the direction of the first peak of the first segment and the first valley of the second segment. The bridge elements may be connected to the segments at points spaced 360&deg; apart along the sinusoidal shape of the segments. The segments and bridge elements are configured such that when compression, flexure, and torsion forces are applied to the stent they generate first maximum stress regions, second maximum stress regions and third maximum stress regions which do not overlap.

Stents for angioplasty

The apparatus comprises an implantation device having a body, the surface of which has at least a portion coated with a receptor, and a preparation containing a ligand formed from the combination of an active principle with a substance capable of binding to the receptor. This preparation may be brought into contact when desired with the implantation device which is, for example, a stent.

Growing community of inventors

Saluggia, Italy

Maria Curcio