Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Sanofi-synthelabo

Maria Bakonyi

Gyorgy Lugosi

Sandor Szoke

Gyorgy Csermely

Tibor Zsolnai

Maria Hima Nee Toth

Istvan Racz

Jeno Ghyczy

Maria Sziladi

Erzsebet Radvany Nee Hegedus

Istvan Szepessy

Antal Gaj{acute Over (a)}ry

Edit Alatty{acute Over (a)}ni

Erzsebet Molnar Nee Bako

Istvan Szepesi

Marianna Csatari Nee Nagy

Tibor Montai

Tamas Kallai

The present invention relates to a process for the preparation of the racemic or optically active compounds of general formula (VI):

Process for the preparation of a pharmacologically active substance

A new process is disclosed for preparing a compound of the formula (I) ##STR1## wherein R is C.sub.1 to C.sub.5 alkyl; which comprises reducing a compound of the formula (II) ##STR2## or salt thereof wherein A is --SO.sub.2 X, --SOH, --SOA.sup.1, or --SA.sup.1 group,

Process for the preparation of benzimidazole-thiol

The invention relates to a new and improved process for the preparation of 6-demethyl-6-deoxy-6-methylene-5-oxytetracycline and the 11a-chloro derivative thereof by dehydrating 11a-chloro-5-oxytetracycline-6,12-hemiketal, which comprises treating 11a-chloro-5-oxytetracycline-6,12-hemiketal or an acid salt thereof with a dehydrating mixture formed by the reaction of chloro sulfonic acid and formic acid and isolating the 11a-chloro-6-demethyl-6-deoxy-6-methylene-5-oxytetracycline and salt thus obtained and optionally dehalogenating the same by reaction with a reducing agent. The advantage of the process of the present invention is that it is simple, economical and suitable for industrial scale manufacture and provides a pure product of high quality by excellent yields.

Process for the preparation of

The invention concerns a new process for the preparation of biologically active 2-[(alkoxycarbonyl)amino]-5-(alkylthio)-1H-benzimidazoles of the general formula (V) ##STR1## wherein R and R.sup.1 independently stand for alkyl having 1 to 3 carbon atoms.

Process for preparing alkylthiobenzimidazoles

The invention relates to a method of combatting phytopathogenic fungi, primarily powdery mildew. The method involves administering compositions according to the invention which contain as active principle at least one compound of the formula (I), ##STR1## wherein R.sup.1 is a C.sub.1-12 alkyl or a chloroethyl group,

Method of treating fungus-infected plants with phenylazocyanoacetic

Compounds of the formula, ##SPC1## Wherein R.sup.1 and R.sup.2 each stand for hydrogen or a group of the general

Water-soluble 1 and/or 2 acid alkylene imidazoles

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Budapest, Hungary

Maria Bakonyi