Agency for Science, Technology and Research

Agresearch Limited

Massey University

Maria Antipina

Maxim Kiryukhin

Hong Yee Low

Harjinder Singh

Gleb Sukhorukov

Karen Chong

Nicole Roy

Gleb B Sukhorukov

Brendan Haigh

Marina Novoselova

Disclosed herein is a core-shell composite material comprising: a core optionally comprising an active ingredient compound; a shell structure comprising at least two alternating layers; the alternating layers being a protein layer and a polyphenol layer; and optionally a polyelectrolyte layer interfacing said core and said shell structure, said polyelectrolyte layer being disposed adjacent to said protein layer or said polyphenol layer, wherein said shell structure is selected to be resistant to degradation under gastric conditions but is degradable by one or more intestinal enzymes. In a preferred embodiment the protein is bovine serum albumin (BSA) or pepsin, the polyphenol layer is tannin or tannic acid, and the shell structure is degradable by pepsin.

Core-shell composite material

The invention provides a microcapsule array comprising a plurality of microcapsules immobilized on a surface, optionally in microwells in said surface. Each of the microcapsules comprises an outer layer or shell defining a microcapsule interior, said outer layer having a permeability towards a nanoscale species which is dependent on an environmental condition to which said array is exposed.

Array of microcapsules for controlled loading of macromolecules, nanoparticles and other nanoscale items and a method of fabricating it

Growing community of inventors

Singapore, Singapore

Maria Antipina