Lytix Biopharma

Mari Wikman

John Sigurd Svendsen

Øystein Rekdal

Nannan Yang

Terese Solstad

The present invention relates to a method of producing a bioactive peptide, wherein the peptide is 7 to 25 amino acids in length, has at least 3 cationic amino acids and is capable of forming an amphipathic &#x3b1;-helix, which method comprises identification of a cationic sector and division of the remaining part of the peptide into three further sectors which are substantially equal in size, and incorporation of at least 60% of the bulk and lipophilicity provided by the amino acid R groups into the sectors flanking the cationic sector; and to uses of the peptides produced thereby in therapy, particularly in the treatment of benign or malignant tumours.

Growing community of inventors

Tromsø, Norway

Mari Wikman